Olorofim

Absorption, Metabolism and Excretion of 14C-olorofim in Man

Drug-drug Interaction (DDI) Study to Assess Effect of Itraconazole and Rifampicin Upon Olorofim

A Biopharmaceutics Study to Assess the Pharmacokinetics of Single Oral and IV Doses of Olorofim

A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment

A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Renal Impairment

Evaluate F901318 (Olorofim) Treatment of Invasive Fungal Infections in Participants Lacking Treatment Options

Olorofim in Early Coccidioidal Meningitis

A Phase II Randomized Study to Evaluate Measures for Endpoint Derivation in Patients With Progressive or Refractory Disseminated Coccidioidomycosis (DCM ) Treated With Olorofim Plus Baseline SOC or Placebo Plus Baseline SOC

Olorofim Aspergillus Infection Study

A Phase III, adjudicator-blinded, randomised study to evaluate the efficacy and safety of treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with invasive fungal disease (IFD) caused by Aspergillus species