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DRUG4 trials

Sponsors

Grupo Espanol De Investigacion En Cancer De Mama, Assistance Publique Hopitaux De Paris, Medical University Of Gdansk, Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicher

Conditions

Adult patients aged 18 and over with unicentric hyalino-vascular Castleman's diseasePatients with invasive breast cancer in early stagesfibrotic interstitial lung diseasesystemic sclerosis with interstitial lung disease (ILD) in the course of the disease

Phase 1

Assessment of the effect of Wharton's jelly mesenchymal stem cell preparation (WJMSCs) in the treatment of fibrotic interstitial lung diseases

RecruitingCTIS2024-514433-38-00

Medical University Of Gdanskfibrotic interstitial lung disease

Start: 2023-09-28Target: 45Updated: 2025-05-13

Phase 2

NUCastle - Nintedanib treatment in Unicentric Castleman disease

Not yet recruitingCTIS2023-510253-42-00

Assistance Publique Hopitaux De ParisAdult patients aged 18 and over with unicentric hyalino-vascular Castleman's disease

Target: 13Updated: 2025-02-05

Phase 3

A multicentre clinical trial evaluating the safety and efficacy of the combination of nintedanib and tocilizumab compared to standard treatment in patients with systemic sclerosis and interstitial lung disease. Analysis with theranostic approach and assessment of cytokine activity, markers of inflammation and pulmonary fibrosis using computed tomography, positron emission tomography, and metabolome and transcriptome studies in selected patients. NINTOC-TU study

RecruitingCTIS2024-517005-85-00

Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reichersystemic sclerosis with interstitial lung disease (ILD) in the course of the disease

Start: 2025-07-01Target: 86Updated: 2024-10-16

Phase 4

LONG-TERM FOLLOW-UP STUDY OF EARLY STAGE BREAST CANCER PATIENTS INCLUDED IN GEICAM STUDIES

RecruitingCTIS2022-502706-33-00

Grupo Espanol De Investigacion En Cancer De MamaPatients with invasive breast cancer in early stages

Start: 2018-01-10Target: 8000Updated: 2025-07-16