NVD003
Sponsors
Novadip Biosciences
Conditions
Congenital Pseudarthrosis of TibiaCongenital pseudarthrosis of the tibiaRecalcitrant Lower Limb Nonunionrecalcitrant lower limb nonunion
Phase 1
Prospective Study in Adults Evaluating Safety & Efficacy of NVD003 for Bone Reconstruction to Treat Lower Limb Nonunion
Active, not recruitingNCT06335394
Start: 2018-08-02End: 2028-05-15Updated: 2024-03-28
A prospective multicentre single-arm study in adults to evaluate the safety and preliminary efficacy of the autologous 3D osteogenic implant NVD-003 for bone reconstruction for the treatment of recalcitrant lower limb nonunion.
RecruitingCTIS2024-517762-42-01
Start: 2018-08-02Target: 11Updated: 2025-09-04
Phase 3
A Study to Assess How Effective and Safe NVD003 is for Treating Patients With Congenital Pseudarthrosis of the Tibia.
RecruitingNCT07112443
Start: 2025-09-02End: 2027-07-01Target: 12Updated: 2026-04-01
A Phase 3 Randomized, Controlled Study to Assess the Efficacy and Safety of NVD003 compared with Iliac Crest Bone Graft in Pediatric Participants Treated Surgically for Congenital Pseudarthrosis of the Tibia
RecruitingCTIS2025-520998-39-00
Start: 2025-11-07Target: 4Updated: 2025-11-07