nucleos(t)ide analogue

DRUG6 trials

Conditions

Chronic HepatitisChronic Hepatitis BChronic Hepatitis bHepatitis BIntermediate to High Risk of HCCTo Evaluate the Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues in Nucleos(t)Ide-treated Patients With Chronic Hepatitis B

Phase 1

Safety, Tolerability, and Pharmacokinetics of AB-836 in Healthy Subjects and Subjects With Chronic HBV Infection

TerminatedNCT04775797

Arbutus Biopharma CorporationChronic Hepatitis

Start: 2021-06-25End: 2022-11-17Updated: 2022-11-21

Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

CompletedNCT05960240

Arbutus Biopharma CorporationChronic Hepatitis b

Start: 2023-08-30End: 2026-02-09Updated: 2026-04-13

Phase 2

Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B

NCT05256823

Lai WeiTo Evaluate the Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues in Nucleos(t)Ide-treated Patients With Chronic Hepatitis B

Start: 2022-02-24End: 2023-12-31Updated: 2022-08-03

Phase 4

PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patients

CompletedNCT01373684

Foundation for Liver ResearchChronic Hepatitis B

Start: 2012-05-25End: 2019-10-28Updated: 2019-11-08

Unknown Phase

Maternal Antiviral Treatment and Infants Immunoprophylaxis in the Prevention of Mother-to-child Transmission

CompletedNCT03977987

Huashan HospitalHepatitis B

Start: 2011-01-01End: 2018-12-30Updated: 2019-06-12

A Prospective Study to Evaluate Peginterferon in Reducing the Incidence of HCC in CHB Patients

RecruitingNCT05671315

Qing XIeChronic Hepatitis B, Intermediate to High Risk of HCC

Start: 2019-07-03End: 2026-04-30Target: 267Updated: 2023-05-25

Antiviral Research2024-04-236 citations

Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study

Clinical Infectious Diseases2019-01-2421 citations