NPH insulin

DRUG18 trials

Sponsors

Sanofi, University of Giessen, Novo Nordisk A/S, Hospital de Clinicas de Porto Alegre, ikfe-CRO GmbH

Conditions

Arterial HypertensionChronic Kidney DiseaseDiabetesDiabetes MellitusDiabetes Mellitus Type 1Diabetes Mellitus, Insulin-DependentDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2

Phase 1

A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus

CompletedNCT02910518

SanofiType1 Diabetes Mellitus

Start: 2017-02-17End: 2017-05-03Updated: 2022-04-25

Phase 3

Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents

CompletedNCT00115570

SanofiDiabetes Mellitus, Insulin-Dependent

Start: 2005-04-30End: 2006-11-30Updated: 2016-05-20

Efficacy and Safety of Insulin Detemir Versus Neutral Protamine Hagedorn (NPH) Insulin in Pregnant Women With Type 1 Diabetes

CompletedNCT00474045

Novo Nordisk A/SDiabetes, Diabetes Mellitus, Type 1

Start: 2007-05-31End: 2010-08-31Updated: 2017-03-10

Efficacy and Safety of Insulin Glargine Versus. Neutral Protamine Hagedorn (NPH) Insulin in Children With Type 1 Diabetes Above 6 Years Old.

CompletedNCT01223131

SanofiType 1 Diabetes Mellitus

Start: 2011-02-28End: 2014-03-31Updated: 2014-04-01

Evaluation of the Efficacy and Safety of Insulin Detemir Compared With That of NPH Insulin in Subjects With Type 1 Diabetes.

CompletedNCT03220425

Novo Nordisk A/SDiabetes Mellitus, Type 1

Start: 2001-02-01End: 2001-11-12Updated: 2017-07-18

Phase 4

Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

CompletedNCT00941148

ikfe-CRO GmbHInsufficient Metabolic Control, OAD Treatment, Type 2 Diabetic Patients

Start: 2008-04-30End: 2009-03-31Updated: 2009-07-17

Basal Analog Study - Comparison of Lantus or Levemir With NPH Insulin From T1DM Diagnosis

Karolinska InstitutetDiabetes Mellitus Type 1

Start: 2005-09-30Updated: 2011-01-06

Establishing Cardiovascular Biomarkers to Define Preferred Lantus® Use

ikfe-CRO GmbHInsulin-requiring Type 2 Diabetes Mellitus

Start: 2011-10-31End: 2012-10-31Target: 60Updated: 2011-12-29

The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients

CompletedNCT01810952

Baylor College of MedicineDiabetes Mellitus, Hyperglycemia

Start: 2010-09-30End: 2013-09-30Updated: 2017-02-08

Glargine Versus NPH in Patients With Chronic Kidney Disease

CompletedNCT02451917

University of Sao Paulo General HospitalChronic Kidney Disease, Type 2 Diabetes Mellitus

Start: 2013-12-31End: 2016-08-31Updated: 2017-12-20

Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D

CompletedNCT02607410

University of Sao Paulo General HospitalType 2 Diabetes Mellitus

Start: 2010-01-31End: 2014-07-31Updated: 2015-11-18

A Real World Trial to Determine Efficacy and Health Outcomes of Toujeo Compared to Standard of Care Basal Insulin in Patients Already Using Basal Insulin

CompletedNCT02967211

SanofiDiabetes Mellitus, Type 2

Start: 2015-12-21End: 2017-10-20Updated: 2022-04-25

A Real World Trial to Determine Efficacy and Health Outcomes of Toujeo Compared to Standard of Care Basal Insulins in Insulin Naïve Patients Initiating Insulin

CompletedNCT02967224

SanofiDiabetes Mellitus, Type 2

Start: 2015-11-05End: 2017-10-16Updated: 2022-04-25

Insulin Schemes for Type 2 Diabetes Control

CompletedNCT03350984

Universidad de GuanajuatoType 2 Diabetes Mellitus

Start: 2017-11-02End: 2018-07-01Updated: 2021-12-06

Use of NPH Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia

TerminatedNCT03511521

Northwestern UniversityHyperglycemia Steroid-induced, Insulin Resistance, Diabetes

Start: 2018-03-27End: 2019-08-15Updated: 2020-09-11

Intermediate and Long Acting Insulin Young Children Type 1 Diabetes.

Ain Shams Universitytype1diabetes, Type 1 Diabetes Mellitus With Hypoglycemia

Start: 2019-02-21End: 2021-03-10Target: 60Updated: 2021-02-16

Unknown Phase

Comparison of Insulin Glargine and NPH Insulin at Night and at Hypoglycemia in Type 2 Diabetes

CompletedNCT00468364

University of GiessenDiabetes

Start: 2003-07-31End: 2006-03-31Updated: 2007-08-30

Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy

Hospital de Clinicas de Porto AlegreArterial Hypertension, Diabetes Mellitus

Start: 2006-07-31End: 2012-07-31Target: 124Updated: 2011-10-26

Related Papers

Real-world outcomes of treatment with insulin glargine 300 U/mL versus standard-of-care in people with uncontrolled type 2 diabetes mellitus

Current Medical Research and Opinion2019-12-2119 citations

Insulin Glargine U100 Improved Glycemic Control and Reduced Nocturnal Hypoglycemia in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease Stages 3 and 4.

2019-08-0220 citations

A randomised, open-labelstudy of insulin glargine or neutral protamine Hagedorn insulin in Chinese paediatric patients with type 1 diabetes mellitus.

2016-11-264 citations

How many unpublished studies? ClinicalTrials.gov (n = 2614 studies): diabetes | Closed Studies | Interventional Studies | Phase 3, 4 | Search Date: Oct 27, 2014

Figshare2014-01-01