NPC-12G gel

DRUG3 trials

Sponsors

Nobelpharma

Conditions

AngiofibromaHypomelanotic MaculeNeurofibromatosisPlaqueTuberous Sclerosis

Phase 3

Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex

CompletedNCT02634931

NobelpharmaAngiofibroma, Hypomelanotic Macule, Plaque +1

Start: 2015-12-31End: 2018-10-31Updated: 2019-02-20

Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)

CompletedNCT02635789

NobelpharmaAngiofibroma, Hypomelanotic Macule, Plaque +1

Start: 2015-12-31End: 2016-10-31Updated: 2017-02-02

A Long-term Study of NPC-12G Gel in Neurofibromatosis Type I

TerminatedNCT04461886

NobelpharmaNeurofibromatosis

Start: 2020-07-08End: 2021-12-07Updated: 2022-05-24

Related Papers

Validation of the Index for Facial Angiofibromas: Data analysis from a randomized controlled trial of sirolimus gel treatment in patients with tuberous sclerosis complex

The Journal of Dermatology2024-04-151 citations

Safety and Efficacy of the Sirolimus Gel for TSC Patients With Facial Skin Lesions in a Long-Term, Open-Label, Extension, Uncontrolled Clinical Trial

Dermatology and Therapy2020-05-0826 citations

Sirolimus Gel Treatment vs Placebo for Facial Angiofibromas in Patients With Tuberous Sclerosis Complex

JAMA Dermatology2018-05-1963 citations