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Normothermic machine perfusion

DEVICE6 trials

Sponsors

Azienda Ospedaliero, Universitaria Pisana, Erasmus Medical Center, Zhang Tianyu, University Medical Center Groningen, Universitair Medisch Centrum Groningen

Conditions

Chronic Kidney FailureEnd Stage Liver DIseaseIschemic Reperfusion InjuryKidney Transplant FailureKidney Transplant; ComplicationsKidney Transplantationend-stage liver disease

Phase 2

Normothermic Machine Perfusion: an Additional Value for Kidney Transplant Outcomes?
Active, not recruitingNCT04882254
Erasmus Medical CenterChronic Kidney Failure, Kidney Transplant Failure
Start: 2021-05-01End: 2025-05-31Updated: 2024-05-07

Unknown Phase

Efficacy Evaluation of Normothermic Perfusion Machine Preservation in Liver Transplant Using Very Old Donors
NCT02940600
Azienda Ospedaliero, Universitaria PisanaIschemic Reperfusion Injury
Start: 2016-10-31End: 2018-10-31Target: 30Updated: 2016-10-21
A single center Phase-I Clinical Trial to Assess Viability of High Risk Donor Livers using Hypothermic and Normothermic Machine Perfusion with Rewarming Phase Prior to Transplantation
Active, not recruitingNL-OMON47272
Universitair Medisch Centrum Groningenend-stage liver disease
Start: 2016-12-01Target: 10Updated: 2024-02-28
Comparison of Hypothermic Versus Normothermic Ex-vivo Preservation.
NCT04744389
Azienda Ospedaliero, Universitaria PisanaEnd Stage Liver DIsease
Start: 2020-12-15End: 2023-03-31Target: 60Updated: 2022-07-26
Normothermic Machine Perfusion (NMP) Versus Hypothermic Machine Perfusion (HMP) in Human Kidney Transplantation
NCT05743751
Zhang TianyuKidney Transplantation
Start: 2023-03-03End: 2025-09-03Target: 60Updated: 2023-02-24
Renal Ex Vivo Warm Advanced Resuscitation Through Machine Perfusion
RecruitingNCT05782543
University Medical Center GroningenKidney Transplant; Complications
Start: 2024-12-15End: 2028-05-01Target: 240Updated: 2025-12-18

Related Papers

(Pro)renin, Erythropoietin, Vitamin D and Urodilatin Release From Human Donor Kidneys During Normothermic Machine Perfusion: Predictors of Early Post‐Transplant Outcome?
Clinical Transplantation2025-04-252 citations
Improved Utilization Rate in Solid Organ Donors ≥80 Years: The 7‐Year Tuscany Experience
Clinical Transplantation2025-03-27
Normothermic machine perfusion versus static cold storage in donation after circulatory death kidney transplantation: a randomized controlled trial
Nature Medicine2023-05-25148 citations
Kidney Preservation Strategies to Improve Transplant Outcomes
Clinical Journal of the American Society of Nephrology2023-05-232 citations
Additional Normothermic Machine Perfusion Versus Hypothermic Machine Perfusion in Suboptimal Donor Kidney Transplantation: Protocol of a Randomized, Controlled, Open-Label Trial
International Journal of Surgery Protocols2021-01-0127 citations