Noradrenaline

DRUG15 trials

Sponsors

Onze Lieve Vrouwe Gasthuis, University Hospital, Clermont-Ferrand, Post Graduate Institute of Medical Education and Research, Chandigarh, Institute of Liver and Biliary Sciences, India, Cambridge University Hospitals NHS Foundation Trust

Conditions

Acute Renal InjuryBrain Injuries, TraumaticCardiac DisorderCardiovascular DiseasesCesarean DeliveryChronic Kidney DiseaseCirrhosis With Septic ShockCoagulation Defect; Acquired

Phase 3

TYPE 2 HEPATORENAL SYNDROME

CompletedNCT01637454

Post Graduate Institute of Medical Education and Research, ChandigarhSafety and Efficacy of Terlipressin and Noradrenaline and Predictive Factors of Response in Type 2 HRS

Start: 2009-01-31End: 2011-12-31Updated: 2012-07-11

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation

RecruitingNCT05014581

University of Turin, ItalyCritical Illness, Respiratory Failure

Start: 2024-08-01End: 2026-04-30Target: 420Updated: 2025-03-28

Therapeutic Study Evaluating the Efficacy of Noradrenaline in the Prevention of Hypotension Related to Intubation for Cardiac or Thoracic Surgery

CompletedNCT05335954

Nantes University HospitalCardiac Disorder, Hypotension

Start: 2022-04-27End: 2023-12-12Updated: 2024-03-07

Early Initiated Vasopressor Therapy in the Emergency Department

RecruitingNCT05931601

Odense University HospitalHypotension, Hypotension and Shock, Hypotension Symptomatic +5

Start: 2023-12-08End: 2027-01-31Target: 320Updated: 2025-07-01

Phase 4

Microcirculation Guided Therapy Versus Standard Treatment of Severe Sepsis

Onze Lieve Vrouwe GasthuisMicrocirculation, Severe Sepsis

Start: 2007-06-30Target: 80Updated: 2008-01-22

Intraoperative Noradrenaline to Control Arterial Pressure (INPRESS Study)

CompletedNCT01536470

University Hospital, Clermont-FerrandControl of Arterial Blood Pressure

Start: 2012-03-31End: 2016-07-31Updated: 2016-10-03

Unknown Phase

Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit

CompletedNCT01836224

Institute of Liver and Biliary Sciences, IndiaCirrhosis With Septic Shock

Start: 2012-10-31End: 2014-09-30Updated: 2016-11-22

To Assess the Efficacy of Early Introduction of a Combination of Low Dose Vasopressin Analogue in Addition to Noradrenaline as a Vasopressor in Patients of Cirrhosis With Septic Shock

CompletedNCT02468063

Institute of Liver and Biliary Sciences, IndiaCirrhosis With Septic Shock

Start: 2015-05-01End: 2017-05-31Updated: 2017-11-06

Evaluating the Effect of Standard-of-care Erythropoiesis-stimulating Agents on Forearm Blood Flow in Nondialysis-dependent Subjects With Anaemia Associated With Chronic Kidney Disease.

CompletedNCT02987465

Cambridge University Hospitals NHS Foundation TrustCardiovascular Diseases, Chronic Kidney Disease

Start: 2017-02-20End: 2018-05-21Updated: 2024-02-07

The Effect of Norepinephrine on Cardiac Output in Patients Undergoing Liver Transplant .

CompletedNCT04376281

Cairo UniversityLiver Transplantation

Start: 2019-12-15End: 2021-10-01Updated: 2021-11-09

The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury

University Medical Centre LjubljanaBrain Injuries, Traumatic, Coagulation Defect; Acquired, Coagulation Defect; Bleeding +2

Start: 2020-09-01End: 2022-09-01Target: 60Updated: 2020-08-17

Acute Renal Injury After Major Elective Non-Cardiac Surgery

CompletedNCT04600271

Istanbul UniversityAcute Renal Injury

Start: 2019-06-01End: 2021-02-01Updated: 2021-09-22

Comparison of Hemodynamic Results of Two Different Fluid Managements

Istanbul UniversityPerioperative Fluid Management

Start: 2022-04-01End: 2023-12-01Target: 40Updated: 2023-10-23

The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension

CompletedNCT05774054

Tanta UniversityHypotension, Norepinephrine, Sepsis

Start: 2021-05-01End: 2023-03-10Updated: 2023-03-24

Prophylactic Perioperative Infusion of Ephedrine Versus Noradrenaline in Patients Undergoing Cesarean Delivery Under Spinal Anesthesia

CompletedNCT07067944

Tanta UniversityCesarean Delivery, Ephedrine, Noradrenaline +2

Start: 2023-07-01End: 2024-03-01Updated: 2025-07-16

Related Papers

Prophylactic norepinephrine infusion to reduce severe hypotension during induction of anaesthesia in patients undergoing cardiac surgery: a randomised controlled single-centre clinical trial.

2025-12-10

Early initiated noradrenaline versus fluid therapy for hypotension and shock in the emergency department (VASOSHOCK): a protocol for a pragmatic, multi-center, superiority, randomized controlled trial.

2025-04-07

Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery

JAMA2017-10-03851 citations

Testing a conceptual model on early opening of the microcirculation in severe sepsis and septic shock

European Journal of Anaesthesiology2014-07-1721 citations

Noradrenaline vs terlipressin in the treatment of type 2 hepatorenal syndrome: a randomized pilot study.

2013-04-2166 citations