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Non-operative Management

OTHER6 trials

Sponsors

DFINE Inc., Mount Sinai Hospital, Canada, University of Missouri-Columbia, Jules Bordet Institute, The Cleveland Clinic

Conditions

AK112AppendicitisCholecystitisCholecystitis, AcuteCholecystitis; GallstoneCovid19Metacarpal FracturePainful Osteoporotic Vertebral Compression Fractures (VCF)

Phase 2

Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer
Active, not recruitingNCT04503694
Jules Bordet InstituteRectal Cancer Stage II, Rectal Cancer Stage III
Start: 2021-03-25End: 2032-12-01Target: 72Updated: 2026-03-27
SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer
Not yet recruitingNCT07162714
Zhejiang Cancer HospitalAK112, Radiation, Rectal Cancer
Start: 2025-09-01End: 2028-12-31Target: 30Updated: 2025-09-09

Phase 4

The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation
WithdrawnNCT01480167
DFINE Inc.Painful Osteoporotic Vertebral Compression Fractures (VCF)
Start: 2011-11-30Updated: 2017-01-20

Unknown Phase

Non-operative Management for Locally Advanced Rectal Cancer
RecruitingNCT03179540
Mount Sinai Hospital, CanadaRectal Neoplasms
Start: 2018-03-16End: 2026-12-31Target: 90Updated: 2024-11-20
Non-operative vs Surgical Treatment of Isolated Non-Thumb Metacarpal Shaft Fractures
TerminatedNCT04001062
University of Missouri-ColumbiaMetacarpal Fracture
Start: 2019-06-12End: 2022-04-15Updated: 2023-06-29
Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
TerminatedNCT04748120
The Cleveland ClinicAppendicitis, Cholecystitis, Cholecystitis, Acute +2
Start: 2020-12-28End: 2021-04-06Updated: 2022-03-14

Related Papers

REGINA: A phase II trial of neoadjuvant regorafenib (Rego) in combination with nivolumab (Nivo) and short-course radiotherapy (SCRT) in intermediate-risk, stage II-III rectal cancer (RC).
Journal of Clinical Oncology2022-01-193 citations