Node-Sparing Radiotherapy plus first-line therapy

COMBINATION_PRODUCT2 trials

Sponsors

Sixth Affiliated Hospital, Sun Yat-sen University

Conditions

Immune Checkpoint TherapyMetastatic Colorectal Cancer (CRC)Metastatic Gastric CarcinomaRadiotherapy

Phase 2

Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC)

RecruitingNCT06958419

Sixth Affiliated Hospital, Sun Yat-sen UniversityImmune Checkpoint Therapy, Metastatic Colorectal Cancer (CRC), Radiotherapy

Start: 2025-05-01End: 2031-12-31Target: 286Updated: 2025-08-07

Node-Sparing Short-Course Radiotherapy Plus First-Line Therapy and PD-1 Inhibitor in Unresectable/Metastastic pMMR/MSS Gastric Cancer (MODIFI-GC)

Not yet recruitingNCT06980389

Sixth Affiliated Hospital, Sun Yat-sen UniversityImmune Checkpoint Therapy, Metastatic Gastric Carcinoma, Radiotherapy

Start: 2025-05-31End: 2028-12-31Target: 176Updated: 2025-05-20