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NM8074

DRUG9 trials

Sponsors

NovelMed Therapeutics

Conditions

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisC3 GlomerulopathyDermatomyositisHealthyIgA NephropathyPNH - Paroxysmal Nocturnal HemoglobinuriaParoxysmal Nocturnal HemoglobinuriaaHUS - Atypical Hemolytic Uremic Syndrome

Phase 1

First-in-Human (FIH) Clinical Study of NM8074 in Healthy Adult Volunteers
CompletedNCT05642546
NovelMed TherapeuticsHealthy
Start: 2020-08-12End: 2022-06-15Updated: 2022-12-08
Study of NM8074 in Adult C3 Glomerulopathy Patients
Not yet recruitingNCT05647811
NovelMed TherapeuticsC3 Glomerulopathy
Start: 2027-05-01End: 2030-07-01Target: 18Updated: 2026-04-13

Phase 2

Study of NM8074 in Adult PNH Patients With Inadequate Response to Soliris
Not yet recruitingNCT05646563
NovelMed TherapeuticsParoxysmal Nocturnal Hemoglobinuria
Start: 2027-01-01End: 2030-08-01Target: 12Updated: 2026-04-13
Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy
Not yet recruitingNCT05646524
NovelMed TherapeuticsParoxysmal Nocturnal Hemoglobinuria
Start: 2026-04-30End: 2028-09-30Target: 12Updated: 2025-03-11
Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy
Not yet recruitingNCT05684159
NovelMed TherapeuticsaHUS - Atypical Hemolytic Uremic Syndrome
Start: 2027-11-01End: 2031-02-01Target: 12Updated: 2026-04-13
Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Not yet recruitingNCT05731050
NovelMed TherapeuticsPNH - Paroxysmal Nocturnal Hemoglobinuria
Start: 2026-06-30End: 2028-03-31Target: 6Updated: 2025-03-30
Study of NM8074 in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)
Not yet recruitingNCT06226662
NovelMed TherapeuticsAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Start: 2026-06-30End: 2028-09-30Target: 12Updated: 2025-03-11
Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN)
Not yet recruitingNCT06454110
NovelMed TherapeuticsIgA Nephropathy
Start: 2028-02-01End: 2031-12-01Target: 10Updated: 2026-04-13
Study of NM8074 in Patients with Dermatomyositis (DM)
Not yet recruitingNCT06887738
NovelMed TherapeuticsDermatomyositis
Start: 2026-06-30End: 2028-12-31Target: 8Updated: 2025-03-25