Nivolumab + Ipilimumab
Sponsors
Prof. Dr. med. Dirk Schadendorf, Intergroupe Francophone de Cancerologie Thoracique, European Organisation for Research and Treatment of Cancer - EORTC, Rennes University Hospital, Institut Claudius Regaud
Conditions
Advanced Kidney CancerAdvanced MelanomaAdvanced Non Small Cell Lung CancerMalignant MelanomaMalignant Melanoma Stage IIIMelanomaMesotheliomaMetastatic Non-small Cell Lung Cancer
Phase 1
Phase 2
Immunotherapy With Nivolumab or Nivolumab Plus Ipilimumab vs. Double Placebo for Stage IV Melanoma w. NED
CompletedNCT02523313
Start: 2015-09-02End: 2021-06-27Updated: 2025-04-09
Nivolumab Monotherapy or Nivolumab Plus Ipilimumab, for Unresectable Malignant Pleural Mesothelioma (MPM) Patients
CompletedNCT02716272
Start: 2016-03-24End: 2019-06-22Updated: 2021-02-10
Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib
Active, not recruitingNCT03235245
Start: 2018-10-30End: 2027-01-31Updated: 2025-08-01
Phase 3
Nivolumab and Ipilimumab Versus Chimiotherapy in First Line Treatment in PS 2 or Elderly in Advanced NSCLC Patients
CompletedNCT03351361
Start: 2018-02-19End: 2022-07-31Updated: 2023-03-01
SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma
RecruitingNCT06794775
Start: 2025-07-10End: 2032-04-15Target: 128Updated: 2025-12-12
The Impact of Time-of-day-Dependent Administration of Nivolumab-Ipilimumab (ICI/ICI) Combination on Overall Survival in Adults With Advanced Kidney Cancer: A Pragmatic Multicenter, Randomized Controlled Trial.
Not yet recruitingNCT07338981
Start: 2026-04-30End: 2032-12-31Target: 142Updated: 2026-01-14
Unknown Phase
A Study to Evaluate First-line Ipilimumab + Nivolumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Active, not recruitingNCT06487156
Start: 2023-10-11End: 2030-10-11Updated: 2026-01-27
Long-term Outcomes Among Patients With Programmed Death-ligand 1 <1% Metastatic Non-small Cell Lung Cancer Treated With First-line Nivolumab + Ipilimumab + 2 Cycles of Chemotherapy
Active, not recruitingNCT07024862
Start: 2024-10-24End: 2025-06-30Target: 100Updated: 2025-06-17
Outcomes of Nivolumab in Combination With Relatlimab in Patients With Advanced Melanoma in the Flatiron Database
CompletedNCT07079644
Start: 2024-11-29End: 2025-03-31Updated: 2025-07-23
Real-world Outcomes Among Patients With Melanoma Treated With Neoadjuvant Nivolumab+Relatlimab or Nivolumab+Ipilimumab
CompletedNCT07091695
Start: 2025-05-11End: 2025-11-06Updated: 2025-11-12
Long-Term Safety Outcomes and First-Line Treatment Patterns in Patients With Non-Small Cell Lung Cancer and Programmed Death-1 (Pd-L1) <1%
Active, not recruitingNCT07215962
Start: 2024-11-22End: 2026-03-01Target: 300Updated: 2025-10-14