Nitrous oxide gas for inhalation

DRUG7 trials

Sponsors

Washington University School of Medicine, University of Michigan, Boston Children's Hospital, University of Chicago, Unity Health Toronto

Conditions

Adolescent HealthAnalgesiaCentral Neuropathic PainContraceptive DevicesFibromyalgiaGynecologyHealthyLong-Acting Reversible Contraception

Phase 2

Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

WithdrawnNCT04089852

Boston Children's HospitalAdolescent Health, Analgesia, Contraceptive Devices +2

Start: 2021-06-01End: 2021-11-01Updated: 2022-09-16

Antidepressant Effects of Nitrous Oxide

WithdrawnNCT05357040

University of ChicagoMajor Depressive Disorder, Treatment Resistant Depression

Start: 2021-06-30End: 2026-02-27Updated: 2026-05-14

Nitrous Oxide as Treatment for Fibromyalgia

WithdrawnNCT05357066

University of ChicagoCentral Neuropathic Pain, Fibromyalgia

Start: 2021-11-12End: 2026-02-27Updated: 2026-05-14

N2O for Acute Suicidality and Depression in the ED

WithdrawnNCT05710887

University of ChicagoMajor Depressive Disorder, Suicidal Ideation, Treatment Resistant Depression

Start: 2026-02-27End: 2026-02-27Updated: 2026-03-04

Phase 4

Nitrous Oxide Treatment for Tinnitus

CompletedNCT03365011

Washington University School of MedicineTinnitus

Start: 2016-10-31End: 2017-07-31Updated: 2018-12-14

Network-Level Effects of Nitrous Oxide in the Human Brain

CompletedNCT03435055

University of MichiganHealthy

Start: 2017-07-21End: 2019-10-11Updated: 2021-11-30

Unknown Phase

SMILE Trial - Imaging Sub-Study

CompletedNCT05528718

Unity Health TorontoMajor Depressive Disorder

Start: 2023-03-07End: 2024-06-14Updated: 2026-03-27

Related Papers

Effect of Nitrous Oxide as a Treatment for Subjective, Idiopathic, Nonpulsatile Bothersome Tinnitus

JAMA Otolaryngology–Head & Neck Surgery2018-08-0211 citations