Nitrogen gas

DRUG7 trials

Sponsors

Mallinckrodt, University of Alabama at Birmingham, University of Florida, Massachusetts General Hospital, Roger Alvarez

Conditions

AnoxemiaBipolar DepressionCOVID-19Covid19Hypertension, Pulmonary, of Newborn, PersistentHypoxemiaHypoxemic Respiratory FailureLiver Injury

Early Phase 1

Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder

Active, not recruitingNCT03748446

Massachusetts General HospitalBipolar Depression, Major Depressive Disorder

Start: 2019-12-05End: 2026-12-01Target: 20Updated: 2026-06-23

S-Nitrosylation Therapy of COVID-19

WithdrawnNCT04528771

James ReynoldsCovid19, SARS-CoV2 Infection

Start: 2021-08-05End: 2025-04-30Updated: 2025-05-07

Phase 2

Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation

CompletedNCT00582010

University of Alabama at BirminghamLiver Injury, Reperfusion Injury

Start: 2008-04-30End: 2012-10-31Updated: 2014-11-06

The Effects of Nitric Oxide for Inhalation in Right Ventricular Infarction Patients

TerminatedNCT00782652

MallinckrodtRight Ventricular Infarction

Start: 2006-03-31End: 2007-02-28Updated: 2016-09-09

iNOPulse for COVID-19

WithdrawnNCT04398290

Roger AlvarezCOVID-19, Hypoxemia, Hypoxemic Respiratory Failure

Start: 2020-12-01End: 2021-07-15Updated: 2020-08-19

Phase 3

Effects of Inhaled Nitric Oxide in the Treatment of Acute Hypoxemic Respiratory Failure (AHRF) in Pediatrics

TerminatedNCT00041561

MallinckrodtAnoxemia, Respiratory Insufficiency

Start: 2002-01-31End: 2004-12-31Updated: 2016-07-26

Phase 4

Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure

WithdrawnNCT01891500

University of FloridaHypertension, Pulmonary, of Newborn, Persistent, Persistent Fetal Circulation Syndrome, Persistent Pulmonary Hypertension of Newborn

Start: 2016-05-31End: 2019-09-19Updated: 2020-01-07

Related Papers

A Randomized Clinical Trial Testing the Anti-Inflammatory Effects of Preemptive Inhaled Nitric Oxide in Human Liver Transplantation

PLoS ONE2014-02-1239 citations