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Nitric Oxide Gas

DRUG5 trials

Sponsors

Xijing Hospital, Massachusetts General Hospital

Conditions

Adult Patients Undergoing Cardiovascular Surgery With Cardiopulmonary BypassCOVID-19COVID19Cardiac SurgeryCardiopulmonary BypassCoronavirusCoronavirus Covid-19 Infection Variant OmicronNitric Oxide

Phase 2

Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.
WithdrawnNCT04290871
Xijing HospitalCoronavirus Covid-19 Infection Variant Omicron, SARS (Severe Acute Respiratory Syndrome)
Start: 2023-01-16End: 2024-04-01Updated: 2023-02-08
Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19
CompletedNCT04306393
Massachusetts General HospitalCoronavirus, SARS (Severe Acute Respiratory Syndrome)
Start: 2020-03-21End: 2022-06-15Updated: 2026-04-01
Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED
TerminatedNCT04338828
Massachusetts General HospitalCOVID19
Start: 2020-04-18End: 2021-03-01Updated: 2022-01-06
Inhaled NO in Surgical Patients With Recent COVID-19 Infection
CompletedNCT05721144
Xijing HospitalCOVID-19, Nitric Oxide, Postoperative Complications +1
Start: 2023-02-17End: 2024-05-07Updated: 2024-05-10

Phase 3

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass
RecruitingNCT06702553
Xijing HospitalAdult Patients Undergoing Cardiovascular Surgery With Cardiopulmonary Bypass, Cardiac Surgery, Cardiopulmonary Bypass +1
Start: 2025-05-19End: 2029-03-31Target: 3650Updated: 2025-07-15

Related Papers

Inhaled Nitric Oxide ReDuce postoperatIve pulmoNAry complicaTions in patiEnts with recent COVID-19 infection (INORDINATE): protocol for a randomised controlled trial
BMJ Open2024-03-011 citations
Right Ventricular Strain Is Common in Intubated COVID-19 Patients and Does Not Reflect Severity of Respiratory Illness
Journal of Intensive Care Medicine2021-03-3036 citations
Transthoracic Echocardiography in Prone Patients With Acute Respiratory Distress Syndrome: A Feasibility Study
Critical Care Explorations2020-08-0125 citations