Nimenrix powder and solvent for solution for injection in pre-filled syringe Meningococcal groups A
Sponsors
Moderna Inc., GlaxoSmithKline Biologicals, Sanofi Pasteur, Sanofi Pasteur Inc., Dianthus Therapeutics Inc.
Conditions
Acute lower respiratory infectionGeneralized Myasthenia GravisHealthy infants receiving a profylactic vaccine to prevent measles infectionHealthy volunteers (Meningococcal infection)InfectionsInvasive meningococcal diseaseMeningococcalMeningococcal immunization
Phase 1
A Phase 1, Randomized, Observer-blind, Placebo-controlled, Age De-escalation Study of the Safety, Tolerability, and Immunogenicity of mRNA-1345 and mRNA-1365 in Participants Aged 5 months to < 24 months
CompletedCTIS2022-502022-41-00
Start: 2024-05-28End: 2024-12-18Target: 248Updated: 2024-09-24
A Phase II, Randomized, Partially Blinded Study to Assess the Safety, Tolerability and Immunogenicity of Meningococcal Combined ABCWY Vaccine when Administered to Healthy Infants
CompletedCTIS2023-506449-40-00
Start: 2021-11-29End: 2025-11-21Target: 497Updated: 2025-09-01
Phase 2
A PHASE 2, RANDOMIZED, BLINDED, PLACEBOCONTROLLED, STUDY TO EVALUATE SAFETY, TOLERABILITY, PHARMACOMETRICS, AND EFFICACY OF DNTH103 IN ADULTS WITH GENERALIZED MYASTHENIA GRAVIS (MAGIC)
RecruitingCTIS2024-512865-15-00
Start: 2024-09-03Target: 54Updated: 2025-10-27
A parallel-group prevention, Phase II, partially blinded, multi-stage study to investigate the immunogenicity and safety of Pentavalent Meningococcal ABCYW Vaccine formulations compared with licensed meningococcal vaccines when administered alone in healthy children (2 to 9 years of age) or concomitantly with routine pediatric vaccines in toddlers (12 to 15 months of age) and infants (2 months of age).
Active, not recruitingCTIS2023-510465-10-00
Start: 2025-03-10Target: 250Updated: 2025-11-13
Phase 3
Phase 4
Primary and booster meningococcal vaccination in Dutch elderly: study to investigate the immune response and determine functional antibodies after the tetravalent MenACWY-TT conjugate vaccine in the elderly population
Active, not recruitingCTIS2024-513640-29-00
Start: 2024-05-13Target: 280Updated: 2025-10-27
EarLy extra Measles immunisation during a measles Outbreak (ELMO)
Not yet recruitingCTIS2024-513395-18-00
Target: 155Updated: 2024-07-22