NGS

GENETIC14 trials

Sponsors

The First Affiliated Hospital, Sun Yat-Sen University, Peking University People's Hospital, Karolinska University Hospital, Shanghai Chest Hospital, Nanfang Hospital, Southern Medical University

Conditions

Adult Acute Lymphoblastic LeukemiaAdult Lymphoblastic LymphomaAutoimmune Hemolytic AnemiaAutoimmune NeutropeniaCerebral PalsyChromosome TranslocationChronic Idiopathic NeutropeniaCold Agglutinin Disease

Early Phase 1

Genomic profiling analysis of clinical sarcomas: a multicenter, non-randomized, open and authentic study

RecruitingChiCTR1900025163

The First Affiliated Hospital, Sun Yat-Sen UniversitySarcoma

Start: 2019-08-12Updated: 2019-08-27

Phase 2

Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL

Nanfang Hospital, Southern Medical UniversityLeukemia, Acute, Leukemia, Lymphoblastic, Leukemia, T Cell

Start: 2016-02-14End: 2020-08-30Target: 70Updated: 2018-06-12

Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL

Nanfang Hospital, Southern Medical UniversityAdult Acute Lymphoblastic Leukemia, Adult Lymphoblastic Lymphoma, Leukemia +5

Start: 2016-02-14End: 2021-05-30Target: 80Updated: 2018-06-21

Unknown Phase

NGS and TME for Evidence-based Treatment of Pancreatic Cancer

CompletedNCT02767700

Karolinska University HospitalPancreatic Ductal Adenocarcinoma

Start: 2016-04-30End: 2018-08-31Updated: 2023-10-24

Precision Diagnosis for Intraoperative Frozen Section of Early Stage Lung Cancer

Shanghai Chest HospitalLung Cancer

Start: 2016-02-29End: 2019-10-31Target: 540Updated: 2016-10-27

Application of targeted deep sequencing of circulating tumor DNA (ctDNA) in clinical evaluation of multiple myeloma

RecruitingChiCTR2000040795

Peking University People's HospitalMultiple Myeloma

Start: 2019-12-14Updated: 2021-04-12

Retrospective Study Using Next Generation Sequencing (NGS) on Biological Samples to Improve Genetic Counseling for Patients With Previously Explored Craniofacial Midline Defects.

CompletedNCT04691414

Rennes University HospitalHoloprosencephaly

Start: 2021-02-10End: 2021-12-06Updated: 2021-12-07

Clinical Value of Next Generation Sequencing in Chinese Childhood Solid Tumors

Yizhuo ZhangPediatric, Solid Tumors, NGS

Start: 2021-08-06End: 2023-08-06Target: 200Updated: 2021-10-13

Genetic Etiology in Patients With Cerebral Palsy

CompletedNCT05123768

University Medical Centre LjubljanaCerebral Palsy, Developmental Delay, Genetic Disease +1

Start: 2021-04-01End: 2022-11-01Updated: 2022-11-02

Investigation and Diagnosis of the Chromosome Variation in Donated/abandoned Blastocyst

CompletedNCT05216068

Chang Gung Memorial HospitalChromosome Translocation, Genetic Disorders in Pregnancy, Recurrent Miscarriage

Start: 2021-12-01End: 2024-11-30Updated: 2025-02-20

Newborn Sequencing Screening in China

Shanghai Children's HospitalNewborns

Start: 2022-08-05End: 2025-12-31Target: 10000Updated: 2022-07-27

NGS in the Diagnosis of Neonatal Diseases

Shanghai Children's HospitalConventional NBS-positive Infants, NICU Infants, Premature Infants

Start: 2022-08-31End: 2024-12-31Target: 1800Updated: 2022-07-27

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia

RecruitingNCT05931718

Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoAutoimmune Hemolytic Anemia, Autoimmune Neutropenia, Chronic Idiopathic Neutropenia +3

Start: 2019-06-01End: 2035-06-30Target: 200Updated: 2024-10-15

Diagnostic Value of Next-Generation Sequencing Analysis in Biliary Tract Tumours

RecruitingNCT06729944

IRCCS Azienda Ospedaliero-Universitaria di BolognaHepatectomy, NGS, Stenosis of Bile Duct

Start: 2023-04-27End: 2026-06-30Target: 50Updated: 2024-12-12

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