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Next Generation Dome Helmet (NGDH)

DEVICE4 trials

Sponsors

Sunnybrook Health Sciences Centre

Conditions

Disorders of ConsciousnessDisorders of Consciousness Due to Severe Brain InjuryOCDObsessive-Compulsive DisorderObsessive-Compulsive Disorder (OCD)Substance Use Disorder (SUD)Treatment-Resistant DepressionTreatment-resistant Depression (TRD)

Unknown Phase

Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression
RecruitingNCT07094789
Sunnybrook Health Sciences CentreTreatment-Resistant Depression, Treatment-resistant Depression (TRD)
Start: 2025-07-11End: 2027-08-31Target: 20Updated: 2025-08-11
Safety and Feasibility of Next-Generation Dome Helmet (NGDH) for Focused Ultrasound Neuromodulation in Substance Use Disorder (SUD)
RecruitingNCT07684976
Sunnybrook Health Sciences CentreSubstance Use Disorder (SUD)
Start: 2026-07-01End: 2028-07-01Target: 20Updated: 2026-07-06
Assessment of Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Disorders of Consciousness
RecruitingNCT07694258
Sunnybrook Health Sciences CentreDisorders of Consciousness, Disorders of Consciousness Due to Severe Brain Injury
Start: 2025-09-10End: 2028-09-01Target: 10Updated: 2026-07-09
Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Treatment Refractory Obsessive Compulsive Disorder (OCD)
RecruitingNCT07704632
Sunnybrook Health Sciences CentreObsessive-Compulsive Disorder, Obsessive-Compulsive Disorder (OCD), OCD
Start: 2025-09-23End: 2027-09-01Target: 20Updated: 2026-07-15