Neuraceq 300 MBq/mL solution for injection
Sponsors
AC Immune S.A., Life Molecular Imaging GmbH, Immungenetics AG, Biogen Idec Research Limited, Eli Lilly & Co.
Conditions
AL AmyloidosisATTR AmyloidosisAlzheimer's DiseaseAlzheimer's diseaseAlzheimer’s DiseaseBrain DiseasesCardiac AmyloidosisCentral Nervous System Diseases
Phase 1
Phase 2
A Phase 2 Theranostic Trial Evaluating the Effects of Thiethylperazine in
Patients Diagnosed with an Early Stage of Alzheimer's disease
CompletedCTIS2022-501137-23-00
End: 2025-12-17Target: 228Updated: 2025-12-08
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Subjects with Mild Cognitive Impairment Due to Alzheimer’s Disease or Mild Alzheimer’s Disease Dementia
WithdrawnCTIS2022-501644-15-00
Target: 327Updated: 2023-02-20
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Subjects with Mild Cognitive Impairment Due to Alzheimer’s Disease or Mild Alzheimer’s Disease Dementia
Active, not recruitingCTIS2022-501644-15-01
Start: 2023-09-28Target: 233Updated: 2025-10-24
A Patient- and Investigator-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Study Participants With Prodromal to Mild Alzheimer’s Disease (AD), Followed by an Open-Label Extension Period
CompletedCTIS2023-506170-12-00
Start: 2021-10-18End: 2025-08-01Target: 251Updated: 2025-09-08
A Phase 2, Parallel Group, Randomized, Double-Blind, Placebo-Controlled, 3-Arm, Multicenter Treatment Study to Evaluate the Efficacy and Safety of GSK4527226 [AL101] Intravenous Infusion Compared with Placebo in Patients with Early Alzheimer’s Disease
Active, not recruitingCTIS2023-505083-11-01
Start: 2024-05-07Target: 140Updated: 2025-12-04
A Phase 2 Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Intravenous Sabirnetug in Early Alzheimer’s Disease
RecruitingCTIS2023-509807-34-00
Start: 2024-08-12Target: 175Updated: 2026-01-21
Phase 3
An open-label, multi-center, non-randomized pivotal Phase 3 study to evaluate the efficacy and safety of [18F]florbetaben Positron Emission Tomography (PET) imaging to diagnose cardiac AL amyloidosis
RecruitingCTIS2022-500186-27-00
Start: 2023-01-11Target: 169Updated: 2026-01-27
I5T-MC-AACQ: Investigating the Effect of Different Donanemab Dosing Regimens on ARIA-E and Amyloid Lowering in Adults with Early Symptomatic Alzheimer’s Disease
CompletedCTIS2022-502268-18-00
End: 2024-03-19Target: 56Updated: 2023-04-07
A multi-center phase 3 study of 18F-florbetaben positron emission tomography/computed tomography (PET-CT) to non-invasively diagnose cardiac AL amyloidosis: the PETAL study.
RecruitingCTIS2024-517942-33-03
Start: 2023-02-04Target: 150Updated: 2025-01-21