Neoadjuvant Chemotherapy (NACT)

DRUG6 trials

Sponsors

Professor Fernando Figueira Integral Medicine Institute, Hubei Cancer Hospital, RenJi Hospital, Fudan University, Shanghai Zhongshan Hospital

Conditions

CTLA4Esophageal CancerHR+/HER2- Breast CancerHypopharyngeal CarcinomaLaryngeal CarcinomaLocally Advanced Cervical CancerOvarian CancerPD1

Phase 2

Short-course HIPEC in Advanced Epithelial Ovarian Cancer

CompletedNCT02249013

Professor Fernando Figueira Integral Medicine InstituteOvarian Cancer

Start: 2015-02-28End: 2021-02-23Updated: 2021-03-18

Neoadjuvant Chemo-immunotherapy Followed by Concurrent Chemoradiotherapy and Immunotherapy in LACC

Not yet recruitingNCT06916117

RenJi HospitalLocally Advanced Cervical Cancer

Start: 2025-04-05End: 2028-12-30Target: 30Updated: 2025-04-08

Combined Chemo-immunotherapy Plus SBRT in Neoadjuvant Treatment for Luminal Subtype Breast Cancer

Not yet recruitingNCT07254858

First Affiliated Hospital of Wenzhou Medical UniversityHR+/HER2- Breast Cancer

Start: 2025-12-31End: 2029-12-30Target: 302Updated: 2025-11-28

Phase 3

Comparing Neoadjuvant Chemotherapy Combined With PD-1 Inhibitor Versus Neoadjuvant Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Carcinoma

Not yet recruitingNCT06957938

Fudan UniversityHypopharyngeal Carcinoma, Laryngeal Carcinoma

Start: 2025-04-28End: 2031-05-01Target: 168Updated: 2025-05-08

Unknown Phase

CNCMT：a Multi-center, Prospective, Single-arm Study

Enrolling by invitationNCT06714084

Hubei Cancer HospitalCTLA4, Locally Advanced Cervical Cancer, PD1

Start: 2024-10-08End: 2026-12-31Target: 20Updated: 2024-12-03

Patient Derived Organoids (PDOs) to Observe the Clinical Consistency of Personalized Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma

RecruitingNCT07054086

Shanghai Zhongshan HospitalEsophageal Cancer

Start: 2025-03-01End: 2026-07-31Target: 30Updated: 2025-07-08

Related Papers

Quality of life in a phase 2 trial of short-course hyperthermic intraperitoneal chemotherapy (HIPEC) at interval debulking surgery for high tumor burden ovarian cancer

Revista do Colégio Brasileiro de Cirurgiões2020-01-018 citations

388 Short-course HIPEC at the time of interval debulking surgery for high tumor burden ovarian cancer: preliminary results of a pioneering clinical trial in brazil

2019-09-01

Neoadjuvant chemotherapy followed by fast-track cytoreductive surgery plus short-course hyperthermic intraperitoneal chemotherapy (HIPEC) in advanced ovarian cancer: preliminary results of a promising all-in-one approach.

2017-12-139 citations

Exploring flow rate selection in HIPEC procedures

Revista do Colégio Brasileiro de Cirurgiões2016-12-017 citations