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Nebulized normal saline

DRUG8 trials

Sponsors

Children's Hospital Medical Center, Cincinnati, Hamad Medical Corporation, Children's Hospital of Eastern Ontario, Cardarelli Hospital, University Of Anbar

Conditions

Acute BronchiolitisAirway ObstructionAsthmaBronchial AsthmaBronchiectasisBronchiolitisExosomesImmune Checkpoint Inhibitors (ICIs)

Phase 1

Exploratory Study on the Efficacy and Safety of Nebulized hUC-MSC-Derived Exosomes for Non-Acute CIP
Not yet recruitingNCT07599111
Zhou ChengzhiExosomes, Immune Checkpoint Inhibitors (ICIs), Mesenchymal Stem Cells +1
Start: 2026-04-01End: 2028-10-01Target: 40Updated: 2026-05-20

Phase 3

Nebulized Magnesium Sulfate in Pediatric Asthma
WithdrawnNCT00522444
Children's Hospital Medical Center, CincinnatiAsthma
Start: 2007-09-30End: 2013-09-30Updated: 2020-09-07
Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.
NCT02455687
Hamad Medical CorporationBronchial Asthma
Start: 2015-06-30End: 2025-01-31Target: 240Updated: 2024-03-22
Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study
CompletedNCT03567473
Children's Hospital of Eastern OntarioBronchiolitis
Start: 2018-12-13End: 2025-05-21Updated: 2025-07-28

Unknown Phase

Nebulized furosemide as adjunctive therapy in patients with stable chronic obstructive pulmonary disease : A randomized controlled trial
Active, not recruitingPACTR202106917652038
Medical Research Institute Alexandria UniversityRespiratory
Start: 2021-07-01Target: 100Updated: 2026-06-22
Impact of High Flow Therapy on Complications Related to Airway Stenting
RecruitingNCT06069817
Cardarelli HospitalAirway Obstruction, Mucus; Plug, Respiratory Infection
Start: 2024-01-01End: 2024-12-31Target: 30Updated: 2024-02-13
Nebulized 3% Hypertonic Saline Versus Normal Saline in Managing Children With Acute Bronchiolitis: A Randomized Controlled Trial
Not yet recruitingNCT07138625
University Of AnbarAcute Bronchiolitis
Start: 2025-10-01End: 2026-03-31Target: 300Updated: 2025-08-24
Hypertonic Saline Inhalation for Nontuberculous Mycobacterial Lung Disease
RecruitingNCT07647575
Taipei Veterans General Hospital, TaiwanBronchiectasis, Nontuberculous Mycobacterial Lung Disease
Start: 2025-10-03End: 2028-07-31Target: 262Updated: 2026-06-15

Related Papers

A randomised controlled trial comparing epinephrine and dexamethasone to placebo in the treatment of infants with bronchiolitis (BIPED study): a statistical analysis plan.
2025-11-12
The probability of reducing hospitalization rates for bronchiolitis with epinephrine and dexamethasone: A Bayesian analysis
PLoS ONE2025-05-16
Remote, real-time expert elicitation to determine the prior probability distribution for Bayesian sample size determination in international randomised controlled trials: Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone (BIPED) study
Trials2022-04-1110 citations