Nebulized normal saline

DRUG7 trials

Sponsors

Children's Hospital Medical Center, Cincinnati, Hamad Medical Corporation, Children's Hospital of Eastern Ontario, Cardarelli Hospital, University Of Anbar

Conditions

Acute BronchiolitisAirway ObstructionAsthmaBronchial AsthmaBronchiolitisExosomesImmune Checkpoint Inhibitors (ICIs)Mesenchymal Stem Cells

Phase 1

Exploratory Study on the Efficacy and Safety of Nebulized hUC-MSC-Derived Exosomes for Non-Acute CIP

Not yet recruitingNCT07599111

Zhou ChengzhiExosomes, Immune Checkpoint Inhibitors (ICIs), Mesenchymal Stem Cells +1

Start: 2026-04-01End: 2028-10-01Target: 40Updated: 2026-05-20

Phase 3

Nebulized Magnesium Sulfate in Pediatric Asthma

WithdrawnNCT00522444

Children's Hospital Medical Center, CincinnatiAsthma

Start: 2007-09-30End: 2013-09-30Updated: 2020-09-07

Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.

Hamad Medical CorporationBronchial Asthma

Start: 2015-06-30End: 2025-01-31Target: 240Updated: 2024-03-22

Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study

CompletedNCT03567473

Children's Hospital of Eastern OntarioBronchiolitis

Start: 2018-12-13End: 2025-05-21Updated: 2025-07-28

Unknown Phase

Nebulized furosemide as adjunctive therapy in patients with stable chronic obstructive pulmonary disease : A randomized controlled trial

Active, not recruitingPACTR202106917652038

Medical Research Institute Alexandria UniversityRespiratory

Start: 2021-07-01Target: 100Updated: 2026-01-27

Impact of High Flow Therapy on Complications Related to Airway Stenting

RecruitingNCT06069817

Cardarelli HospitalAirway Obstruction, Mucus; Plug, Respiratory Infection

Start: 2024-01-01End: 2024-12-31Target: 30Updated: 2024-02-13

Nebulized 3% Hypertonic Saline Versus Normal Saline in Managing Children With Acute Bronchiolitis: A Randomized Controlled Trial

Not yet recruitingNCT07138625

University Of AnbarAcute Bronchiolitis

Start: 2025-10-01End: 2026-03-31Target: 300Updated: 2025-08-24

Related Papers

A randomised controlled trial comparing epinephrine and dexamethasone to placebo in the treatment of infants with bronchiolitis (BIPED study): a statistical analysis plan.

2025-11-12

The probability of reducing hospitalization rates for bronchiolitis with epinephrine and dexamethasone: A Bayesian analysis

PLoS ONE2025-05-16

Remote, real-time expert elicitation to determine the prior probability distribution for Bayesian sample size determination in international randomised controlled trials: Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone (BIPED) study

Trials2022-04-1110 citations