Near infrared camera imaging system

DEVICE5 trials

Sponsors

On Target Laboratories, LLC, Sunil Singhal

Conditions

Lung CancerLung NeoplasmsLung NoduleNon Small Cell Lung CancerOvarian Cancer

Phase 1

Intraoperative Imaging of Pulmonary Nodules by SGM-101

CompletedNCT04315467

Sunil SinghalLung Cancer, Lung Nodule, Non Small Cell Lung Cancer

Start: 2020-07-08End: 2022-02-10Updated: 2022-06-16

Phase 2

Phase 2 Study of OTL38 for Intra-operative Imaging of Folate Receptor-alpha Positive Ovarian Cancer

CompletedNCT02317705

On Target Laboratories, LLCOvarian Cancer

Start: 2014-12-31End: 2015-11-30Updated: 2022-06-21

OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules

CompletedNCT02872701

On Target Laboratories, LLCLung Cancer, Lung Neoplasms

Start: 2017-05-04End: 2018-11-30Updated: 2023-03-24

Phase 3

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

CompletedNCT03180307

On Target Laboratories, LLCOvarian Cancer

Start: 2018-01-26End: 2020-10-16Updated: 2022-02-04

ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting

CompletedNCT04241315

On Target Laboratories, LLCLung Cancer, Lung Neoplasms

Start: 2020-03-26End: 2021-11-01Updated: 2023-03-23

Related Papers

Intraoperative Molecular Imaging With Pafolacianine in Resection of Occult Pulmonary Malignancy in the ELUCIDATE Trial.

2024-10-212 citations

Carcinoembryonic Antigen–Related Cell Adhesion Molecule Type 5 Receptor–Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer

JAMA Network Open2023-01-2715 citations

Phase 3, randomized, single-dose, open-label study to investigate the safety and efficacy of pafolacianine sodium injection (OTL38) for intraoperative imaging of folate receptor positive ovarian cancer.

Journal of Clinical Oncology2021-05-2023 citations

An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas.

2018-02-0529 citations