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Nanoplexed Poly I:C BO-112

BIOLOGICAL2 trials

Sponsors

Jonsson Comprehensive Cancer Center

Conditions

Advanced Hepatocellular CarcinomaBCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaLeiomyosarcomaMalignant Peripheral Nerve Sheath TumorMyxofibrosarcomaPleomorphic RhabdomyosarcomaRefractory Hepatocellular Carcinoma

Early Phase 1

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer
TerminatedNCT04777708
Jonsson Comprehensive Cancer CenterAdvanced Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma +1
Start: 2021-10-13End: 2023-03-13Updated: 2023-03-24

Phase 1

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma
Active, not recruitingNCT04420975
Jonsson Comprehensive Cancer CenterLeiomyosarcoma, Malignant Peripheral Nerve Sheath Tumor, Myxofibrosarcoma +27
Start: 2020-10-14End: 2028-01-31Updated: 2026-03-10

Related Papers

Abstract CT221: A phase I study of intratumoral BO-112 and nivolumab for resectable soft tissue sarcoma
Cancer Research2021-07-013 citations