NanoKnife

DEVICE19 trials

Sponsors

Aalborg University Hospital, Fuda Cancer Hospital, Guangzhou, Poitiers University Hospital, University of California, San Diego, Englewood Hospital and Medical Center

Conditions

Esophageal NeoplasmsExtremities NeoplasmsGallbladder NeoplasmsHead and Neck NeoplasmsHepatic CarcinomaHilus Pulmonary NeoplasmsInterventional ImagingLaryngeal Neoplasms

Phase 1

Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer

RecruitingNCT06205849

University of California, San DiegoPancreatic Cancer

Start: 2024-07-17End: 2030-08-01Target: 18Updated: 2026-06-25

Unknown Phase

Electroporation (NanoKnife) as Treatment for Advanced Pancreatic Cancer

CompletedNCT02079623

Aalborg University HospitalPancreatic Cancer

Start: 2013-11-30End: 2019-05-01Updated: 2020-01-10

Percutaneous Irreversible Electroporation to Treat Liver Cancer Close to the Gallbladder

CompletedNCT02332551

Fuda Cancer Hospital, GuangzhouHepatic Carcinoma

Start: 2015-01-01End: 2021-08-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Head and Neck Neoplasms

CompletedNCT02335112

Fuda Cancer Hospital, GuangzhouHead and Neck Neoplasms

Start: 2015-01-01End: 2021-01-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Rectal Neoplasms

CompletedNCT02425059

Fuda Cancer Hospital, GuangzhouRectal Neoplasms

Start: 2015-01-01End: 2021-02-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Lung Neoplasms Accompanied by Respiratory Function Insufficiency

CompletedNCT02430753

Fuda Cancer Hospital, GuangzhouLung Neoplasms Accompanied by Respiratory Function Insufficiency

Start: 2015-01-01End: 2021-02-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Urinary Bladder Neoplasms

CompletedNCT02430623

Fuda Cancer Hospital, GuangzhouUrinary Bladder Neoplasms

Start: 2015-01-01End: 2021-03-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Gallbladder Neoplasms

CompletedNCT02430662

Fuda Cancer Hospital, GuangzhouGallbladder Neoplasms

Start: 2015-01-01End: 2021-03-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Hilus Pulmonis Neoplasms

CompletedNCT02430597

Fuda Cancer Hospital, GuangzhouHilus Pulmonary Neoplasms

Start: 2015-01-01End: 2021-03-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Prostatic Neoplasms

WithdrawnNCT02430649

Fuda Cancer Hospital, GuangzhouProstatic Neoplasms

Start: 2015-01-01End: 2025-01-01Updated: 2020-05-27

Irreversible Electroporation(IRE) For Unresectable Stomach Neoplasms

CompletedNCT02430636

Fuda Cancer Hospital, GuangzhouStomach Neoplasms

Start: 2015-01-01End: 2021-02-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Uterine Cervical Neoplasms

CompletedNCT02430610

Fuda Cancer Hospital, GuangzhouUterine Cervical Neoplasms

Start: 2015-01-01End: 2021-02-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Lymph Node Metastases(Close to Nerve)

CompletedNCT02430766

Fuda Cancer Hospital, GuangzhouLymph Node Metastases

Start: 2015-01-01End: 2021-02-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Extremities Neoplasms

CompletedNCT02430688

Fuda Cancer Hospital, GuangzhouExtremities Neoplasms

Start: 2015-01-01End: 2021-02-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Esophageal Neoplasms

CompletedNCT02430701

Fuda Cancer Hospital, GuangzhouEsophageal Neoplasms

Start: 2015-01-01End: 2021-04-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms

CompletedNCT02430675

Fuda Cancer Hospital, GuangzhouLaryngeal Neoplasms

Start: 2015-01-01End: 2021-01-01Updated: 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Renal Pelvic and Ureteral Neoplasms

CompletedNCT02430779

Fuda Cancer Hospital, GuangzhouRenal Pelvic and Ureteral Neoplasms

Start: 2015-01-01End: 2021-01-01Updated: 2021-09-05

Irreversible Electroporation (NanoKnife) for the Treatment of Pancreatic Adenocarcinoma

CompletedNCT03105921

Poitiers University HospitalInterventional Imaging, Pancreatic Adenocarcinoma

Start: 2014-10-24End: 2021-04-01Updated: 2022-03-31

Outcomes of Ablation of Unresectable Pancreatic Cancer Using the NanoKnife Irreversible Electroporation System-

RecruitingNCT06937996

Englewood Hospital and Medical CenterPancreatic Cancer Non-resectable

Start: 2025-05-13End: 2035-05-31Target: 25Updated: 2025-06-17

Related Papers

Abstract CT089: Irreversible electroporation (IRE) with intratumoral CD40 antibody increases T-cell reactivity to personalized neoantigens in locally advanced pancreatic cancer

Cancer Research2026-04-17

Intra-tumoral CD40 antibody with irreversible electroporation (IRE) in locally advanced pancreas cancer.

Journal of Clinical Oncology2025-01-271 citations

Irreversible electroporation to bring initially unresectable locally advanced pancreatic adenocarcinoma to surgery: the IRECAP phase II study.

2024-03-186 citations