Nanocrystalline Megestrol Acetate

DRUG5 trials

Sponsors

Henan Cancer Hospital, Guangzhou Institute of Respiratory Disease, Changchun GeneScience Pharmaceutical Co., Ltd., Nanfang Hospital, Southern Medical University

Conditions

AnorexiaCachexiaCancer - Associated Anorexia - Cachexia SyndromeClinical Characteristics and Treatment Outcomes of Malignant Tumor CachexiaExtensive-stage Small Cell Lung Cancer (ES-SCLC)Hepatocellular CarcinomaHepatocellular Carcinoma (HCC)Malnutrition

Phase 2

Nanocrystalline Megestrol + Immunochemo As 1st-Line for ES-SCLC Cachexia

Not yet recruitingNCT06793228

Henan Cancer HospitalSCLC, Extensive Stage

Start: 2025-01-15End: 2027-12-15Target: 250Updated: 2025-01-27

Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Cancer: A Prospective, Open-Label, Single-Arm Phase II Clinical Study

Not yet recruitingNCT06909383

Guangzhou Institute of Respiratory DiseaseCancer - Associated Anorexia - Cachexia Syndrome, Extensive-stage Small Cell Lung Cancer (ES-SCLC)

Start: 2025-06-01End: 2026-12-31Target: 41Updated: 2025-04-03

Nanocrystalline Megestrol Acetate Versus Placebo for Anorexia in Patients With Unresectable Hepatocellular Carcinoma Receiving TACE Combined With Targeted and Immunotherapy

Not yet recruitingNCT07565415

Nanfang Hospital, Southern Medical UniversityAnorexia, Cachexia, Hepatocellular Carcinoma (HCC) +1

Start: 2026-06-22End: 2027-09-01Target: 88Updated: 2026-05-04

Phase 3

Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma

Not yet recruitingNCT07356037

Changchun GeneScience Pharmaceutical Co., Ltd.Cachexia, Hepatocellular Carcinoma

Start: 2026-01-10End: 2027-12-31Target: 68Updated: 2026-01-21

Phase 4

A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia

RecruitingNCT07243379

Changchun GeneScience Pharmaceutical Co., Ltd.Clinical Characteristics and Treatment Outcomes of Malignant Tumor Cachexia, Multicenter Observational Study

Start: 2025-09-25End: 2027-06-30Target: 495Updated: 2025-11-21