Naltrexone Hydrochloride

DRUG16 trials

Sponsors

Centrum Medycznego Ksztalcenia Podyplomowego, US Department of Veterans Affairs, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), University of Miami, Ensysce Biosciences

Conditions

Alcohol DependenceAnorexia Nervosa, AtypicalAnorexia Nervosa, Binge Eating/Purging TypeAnorexia Nervosa/BulimiaAnorexia in AdolescenceBariatric Surgery PatientsBipolar DisorderBulimia Nervosa

Early Phase 1

Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

RecruitingNCT05007561

San Diego State UniversityNaltrexone, Placebo

Start: 2021-11-16End: 2027-07-31Target: 210Updated: 2025-04-11

Phase 1

Optimizing Pharmacotherapy for Bipolar Alcoholics

CompletedNCT00302133

University of MiamiAlcohol Dependence, Bipolar Disorder

Start: 2006-05-31End: 2013-07-31Updated: 2016-05-17

Study of PF614 Compared to OxyContin® in Healthy Volunteers (PF614-101)

CompletedNCT02454712

Ensysce BiosciencesHealthy

Start: 2016-11-16End: 2018-01-18Updated: 2024-10-02

The Evaluation of Safety and Tolerance of Commercially Available Naltrexone Administered Daily - Assessment for CBRN Operations

CompletedNCT03879460

Timothy SmithOpioid Intoxication

Start: 2019-03-18End: 2019-03-31Updated: 2019-05-17

Evaluation of Oral PF614 Relative to OxyContin (PF614-102)

CompletedNCT05043766

Ensysce BiosciencesHealthy Volunteers

Start: 2021-09-08End: 2022-03-21Updated: 2024-09-24

Pharmacokinetics of Oxycodone and PF614 Co-Administered with Nafamostat (PF614-MPAR-101)

CompletedNCT05090280

Ensysce BiosciencesPharmacokinetics

Start: 2021-12-01End: 2023-04-26Updated: 2024-09-24

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

RecruitingNCT07224087

Yale UniversityBariatric Surgery Patients, Obesity, Smoking Cessation

Start: 2026-03-02End: 2027-12-31Target: 20Updated: 2026-03-19

A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

Not yet recruitingNCT07398404

Yale UniversityBariatric Surgery Patients, Obesity, Smoking Cessation

Start: 2026-07-01End: 2031-06-30Target: 64Updated: 2026-03-20

Phase 2

Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

CompletedNCT03482479

University of PennsylvaniaChurg-Strauss Syndrome (CSS), Eosinophilic Granulomatosis With Polyangiitis (EGPA), Giant Cell Arteritis +4

Start: 2019-02-04End: 2025-12-31Updated: 2026-01-22

Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM

CompletedNCT04791969

Glenn-Milo SantosMethamphetamine Use Disorder

Start: 2021-12-14End: 2024-07-01Updated: 2025-10-27

Oral Naltrexone In Pediatric Eating Disorders

TerminatedNCT05073679

Rosemary Claire RodenAnorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type +6

Start: 2022-04-22End: 2024-05-21Updated: 2025-08-19

Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia

RecruitingNCT05955313

Medical University of LublinNaltrexone, Quality of Life, Vulvodynia

Start: 2023-05-31End: 2026-12-31Target: 300Updated: 2023-07-21

Phase 3

Self-Injury: Diagnosis and Treatment

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Mental Retardation, Self-Injurious Behavior

Start: 1997-07-31End: 2002-06-30Target: 37Updated: 2005-06-24

Pharmacological treatment of compulsive sexual behaviour disorder

RecruitingCTIS2024-514490-22-01

Centrum Medycznego Ksztalcenia PodyplomowegoCompulsive Sexual Behaviour Disorder

Start: 2025-06-12Target: 410Updated: 2026-01-19

Unknown Phase

Naltrexone and Patch for Smokers

CompletedNCT00018213

US Department of Veterans AffairsSmoking

Start: 1998-04-30End: 2001-03-31Updated: 2009-01-21

The Use of Naltrexone Hydrochloride to Promote Healing in Patients With Resistant Non-infectious Corneal Ulcer

CompletedNCT05924893

Minia UniversityCornea Ulcer

Start: 2021-01-01End: 2022-12-15Updated: 2023-06-29

Related Papers

Pelvic floor examination in vulvodynia: VAMP protocol validation in correlation with central sensitization

Women s Health2025-07-011 citations