Nalmefene HCl injection

DRUG2 trials

Sponsors

Leiden University Medical Center, Purdue Pharma LP

Conditions

Chronic Opioid UseOpioid Induced Respiratory DepressionOpioid Overdose

Phase 1

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists

TerminatedNCT05338632

Leiden University Medical CenterOpioid Induced Respiratory Depression, Chronic Opioid Use

Start: 2022-06-24End: 2026-03-23Updated: 2026-07-29

Pharmacodynamic Evaluation of Intramuscular Nalmefene Autoinjector 1.5 mg Compared to Intranasal Narcan 4 mg

CompletedNCT06719986

Purdue Pharma LPOpioid Overdose

Start: 2022-10-03End: 2022-12-23Updated: 2025-07-03