NAC

DRUG15 trials

Sponsors

United States Army Research Institute of Environmental Medicine, Merck Sharp & Dohme LLC, Suleyman Demirel University, Woman's Health University Hospital, Egypt, Otologic Pharmaceutics, Inc.

Conditions

Abnormal Blood Oxygen PressureAcute ST Segment Elevation Myocardial InfarctionAdultsAllergic RhinitisAllergic RhinoconjunctivitisAseptic Muscle InjuryBreast CancerCarpal Tunnel Surgery

Early Phase 1

NAC Prevents Toxicity of Teeth Bleaching

CompletedNCT03534115

University of California, Los AngelesRemoval of Toxicity From Dental Bleaching

Start: 2014-12-04End: 2017-10-26Updated: 2018-05-23

Phase 1

MK-8237 (SCH900237) Biomarker Study in Participants With Allergic Rhinitis or Rhinoconjunctivitis (MK-8237-009)

CompletedNCT01852825

Merck Sharp & Dohme LLCAllergic Rhinitis, Allergic Rhinoconjunctivitis

Start: 2013-11-27End: 2015-08-03Updated: 2019-03-15

Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC

CompletedNCT02259595

Otologic Pharmaceutics, Inc.Hearing Loss, Noise-Induced Hearing Loss, Sensorineural Hearing Loss

Start: 2014-10-31End: 2015-02-28Updated: 2015-05-01

Study to Evaluate the Feasibility of 13-C Pyruvate Imaging in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

WithdrawnNCT03121989

Sunnybrook Health Sciences CentreBreast Cancer

Start: 2017-11-21End: 2023-03-23Updated: 2023-03-30

Phase 2

the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy

CompletedNCT05485558

Tanta UniversityDrug Resistant Epilepsy

Start: 2022-09-15End: 2025-01-01Updated: 2025-07-01

A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers

RecruitingNCT05509153

Western Sydney Local Health DistrictHuntington Disease

Start: 2024-06-01End: 2027-05-01Target: 160Updated: 2025-02-28

NAC-REPAIR for Post-surgical Pain

Not yet recruitingNCT07227649

University of ArizonaCarpal Tunnel Surgery, De Quervain Syndrome, Dupuytren Contracture +6

Start: 2026-01-15End: 2027-07-15Target: 80Updated: 2025-11-14

Phase 3

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Active, not recruitingNCT01878344

Suleyman Demirel UniversityAcute ST Segment Elevation Myocardial Infarction

Start: 2013-01-31End: 2026-12-31Updated: 2025-05-20

Phase 4

Induced Changes in Ventilatory Responsiveness and Altitude Exposure

TerminatedNCT01241513

United States Army Research Institute of Environmental MedicineAbnormal Blood Oxygen Pressure, Effects of High Altitude, Hypoxia +1

Start: 2010-11-01End: 2013-02-28Updated: 2020-04-30

Clomiphene Plus N-acetyl Cysteine for Induction of Ovulation in Newly Diagnosed Pcos.

CompletedNCT01896492

Woman's Health University Hospital, EgyptPCOS

Start: 2011-01-31End: 2013-06-30Updated: 2020-08-12

NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial

CompletedNCT02483143

Karadeniz Technical UniversityPulmonary Embolism, Radiographic Contrast Agent Nephropathy

Start: 2014-02-28End: 2015-02-28Updated: 2015-06-26

Unknown Phase

Effect of Nano-structured Alumina Coating on the Bond Strength of Zirconia Resin-bonded Fixed Dental Prostheses

University of Ljubljana, Faculty of MedicineAdults, Children, Debonding +2

Start: 2018-01-03End: 2024-03-01Target: 50Updated: 2023-05-11

Pharmacokinetic Profile of N-Acetyl Cysteine

CompletedNCT06252519

University of MemphisPharmacokinetics

Start: 2023-09-18End: 2024-05-22Updated: 2024-12-16

Effects of Protein and NAC Co-ingestion on Skeletal Muscle Recovery

RecruitingNCT06367413

University of ThessalyAseptic Muscle Injury

Start: 2024-04-08End: 2025-07-30Target: 30Updated: 2025-06-04

A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma

Active, not recruitingNCT07155044

Changhai HospitalUC (Urothelial Cancer), UTUC

Start: 2024-05-15End: 2029-05-15Target: 120Updated: 2025-09-04