N-acetyl-L-cysteine

DRUG5 trials

Sponsors

Virginia Commonwealth University, Institute of Liver and Biliary Sciences, India, Peking University People's Hospital

Conditions

Acute Liver FailureAcute Myeloid LeukemiaHaploidentical Hematopoietic Stem Cell TransplantationNeuropathic PainStem Cell Transplant Complications

Phase 2

The Role of N-acetyl-l-cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients With Chronic Neuropathic Pain

CompletedNCT01840345

Virginia Commonwealth UniversityNeuropathic Pain

Start: 2014-01-31End: 2017-04-01Updated: 2018-05-14

Effect of NAC on the Hematopoietic Reconstitution After Haploidentical Hematopoietic Stem Cell Transplantation

CompletedNCT03236220

Peking University People's HospitalHaploidentical Hematopoietic Stem Cell Transplantation

Start: 2017-08-01End: 2018-12-01Updated: 2020-09-17

NAC for Promoting Hematopoietic Recovery in Patients With Acute Myeloid Leukemia After Chemotherapy

Active, not recruitingNCT06024031

Peking University People's HospitalAcute Myeloid Leukemia

Start: 2023-09-10End: 2025-09-01Target: 30Updated: 2024-11-07

Phase 3

Risk Stratification-directed NAC for Prevention of Poor Hematopoietic Reconstitution

Peking University People's HospitalStem Cell Transplant Complications

Start: 2018-10-01End: 2024-10-01Updated: 2021-09-14

Unknown Phase

High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure

CompletedNCT02718079

Institute of Liver and Biliary Sciences, IndiaAcute Liver Failure

Start: 2016-12-30End: 2018-10-18Updated: 2019-11-20

Related Papers

N-acetyl-L-cysteine promoted hematopoietic recovery in patients with acute myeloid leukemia after complete remission--A pilot study.

2025-05-20

P1417: PROPHYLACTIC NAC PROMOTED HEMATOPOIETIC RECONSTITUTION BY IMPROVING ENDOTHELIAL CELLS AFTER HSCT: A PHASE 3, OPEN-LABEL RANDOMIZED TRIAL

HemaSphere2022-06-01

Prophylactic NAC promoted hematopoietic reconstitution by improving endothelial cells after haploidentical HSCT: a phase 3, open-label randomized trial

BMC Medicine2022-04-2727 citations

Standard-Volume Plasma Exchange Improves Outcomes in Patients With Acute Liver Failure: A Randomized Controlled Trial.

2021-01-29103 citations

Prophylactic oral NAC reduced poor hematopoietic reconstitution by improving endothelial cells after haploidentical transplantation

Blood Advances2019-04-2363 citations