Myeloablative Conditioning

PROCEDURE4 trials

Sponsors

European Society for Blood and Marrow Transplantation, City of Hope Medical Center, Children's Oncology Group

Conditions

Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAcute Myeloid LeukemiaB-Cell Non-Hodgkin LymphomaChronic Lymphocytic LeukemiaChronic Phase Chronic Myeloid Leukemia, BCR-ABL1 PositiveDiffuse Large B-Cell LymphomaHematopoietic and Lymphatic System Neoplasm

Phase 1

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

RecruitingNCT05432635

City of Hope Medical CenterB-Cell Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma +5

Start: 2023-08-01End: 2028-12-30Target: 15Updated: 2026-02-23

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

RecruitingNCT07020533

City of Hope Medical CenterAccelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia +9

Start: 2026-05-08End: 2030-02-14Target: 46Updated: 2026-03-27

Phase 3

Dose-reduced Versus Standard Conditioning in MDS/sAML

TerminatedNCT01203228

European Society for Blood and Marrow TransplantationMyelodysplastic Syndromes, Secondary Acute Myeloid Leukemia

Start: 2004-05-31End: 2015-02-28Updated: 2015-04-03

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Active, not recruitingNCT05457556

Children's Oncology GroupAcute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia +1

Start: 2023-03-15End: 2026-06-30Target: 435Updated: 2025-12-22

Related Papers

Reduced Intensity Vs. Myeloablative Conditioning Followed By Allogeneic Stem Cell Transplantation for Patients with Myelodysplastic Syndrome: Long Term Follow-up of a Prospective Randomized EBMT Phase III Study (RICMAC-Trial)

Blood2018-11-294 citations