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Mycofit

DRUG5 trials

Sponsors

AstraZeneca AB

Conditions

Advanced or Metastatic Non-Small Cell Lung CancerLocally advanced cervical cancerMetastatic Non-Small Cell Lung Cancer (mNSCLC)NSQ NSCLCSQSolid TumorsUnresectable Pleural Mesothelioma

Phase 2

Phase 3

A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination with Carboplatin plus Pemetrexed Versus Platinum plus Pemetrexed or Nivolumab plus Ipilimumab in Participants with Unresectable Pleural Mesothelioma (eVOLVE-Meso)
Active, not recruitingCTIS2023-503231-17-00
AstraZeneca ABUnresectable Pleural Mesothelioma
Start: 2024-04-26Target: 383Updated: 2025-12-12
A Phase III, Two- Arm, Parallel, Randomized, Multi-Center, Open‑Label, Global Study to Determine the Efficacy of Volrustomig (MEDI5752) in Combination with Chemotherapy Versus Pembrolizumab Plus Chemotherapy for First-Line Treatment of Patients with Metastatic Non-Small Cell Lung Cancer (mNSCLC) (eVOLVE-Lung02)
SuspendedCTIS2023-503298-39-00
AstraZeneca ABMetastatic Non-Small Cell Lung Cancer (mNSCLC)
Start: 2024-06-13Target: 437Updated: 2025-12-15
A Phase III, Open-label, Randomised, Multicentre Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Without Actionable Genomic Alterations, and Whose Disease Has Progressed On or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy: LATIFY
Active, not recruitingCTIS2023-509429-37-00
AstraZeneca ABAdvanced or Metastatic Non-Small Cell Lung Cancer
Start: 2022-10-03Target: 520Updated: 2025-08-29
A Phase III, Randomized, Double blind, Placebo controlled, Multi centre, Global Study of Volrustomig in Women with High Risk Locally Advanced Cervical Cancer Who Have Not Progressed Following Platinum based, Concurrent Chemoradiation Therapy (eVOLVE Cervical)
RecruitingCTIS2023-504374-38-00
AstraZeneca ABLocally advanced cervical cancer
Start: 2024-04-12Target: 101Updated: 2025-09-25