MVASI 25 mg/mL concentrate for solution for infusion
Sponsors
CHUR Of Besançon, Centre Hospitalier Regional Universitaire, Immunogen Inc., Centre Hospitalier Universitaire De Grenoble, Arcagy Gineco, Vall D Hebron Institute Of Oncology
Conditions
Advanced ovarianGlioblastomaMetastatic colorectal cancerPatients with locally advancedPersistentPlatinum-sensitive epithelial ovarianRecurrentfallopian tube
Phase 1
Phase 2
TERTIO : Evaluation of the interest to combine a CD4 Th1-inducer cancer vaccine derived from telomerase
and atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma: a proof of concept randomized phase II study
RecruitingCTIS2022-500643-20-00
Start: 2022-09-27Target: 104Updated: 2025-11-13
Ezurpimtrostat autophagy inhibitor in association with Atezolizumab-Bevacizumab in first line treatment of unresectable hepatocellular carcinoma, a phase 2b randomized trial. ABE-LIVER
CompletedCTIS2022-502078-17-00
Start: 2022-12-15End: 2024-03-08Target: 196Updated: 2023-08-22
Bevacizumab plus encorafenib-cetuximab in BRAF-V600E mutated metastatic colorectal cancer, a phase II study with a safety lead-in cohort, the BRAVE trial
RecruitingCTIS2023-509204-15-00
Start: 2024-05-17Target: 94Updated: 2025-10-31
A Randomized Study of Paclitaxel – Carboplatin followed by maintenance Niraparib compared to Paclitaxel – Carboplatin – Bevacizumab followed by maintenance Niraparib + Bevacizumab in Patients With Advanced Ovarian Cancer Following a Front-Line Complete Cytoreductive Surgery (NIRVANA-1 study)
RecruitingCTIS2023-504166-37-00
Start: 2022-02-01Target: 336Updated: 2025-11-07
Phase 3
2022-501606-35-00 – Randomized, multicenter, open-label, Phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab (GLORIOSA).
RecruitingCTIS2022-501606-35-01
Start: 2024-02-21Target: 110Updated: 2026-01-21
A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab With or Without Bevacizumab Compared With Standard of Care as Firstline Maintenance Treatment for Participants With Persistent, Recurrent, or Newly Diagnosed Metastatic Cervical Cancer With PD-L1 CPS Greater Than or Equal to 1 (TroFuse-036/GOG-3123/ENGOT-cx22)
Not yet recruitingCTIS2025-521514-26-00
Target: 317Updated: 2026-01-19