MVA.tHIVconsv4

BIOLOGICAL5 trials

Sponsors

University of North Carolina, Chapel Hill, National Institute of Allergy and Infectious Diseases (NIAID), Henry M. Jackson Foundation for the Advancement of Military Medicine, University of Oxford

Conditions

ARTAcute HIV InfectionHIVHIV InfectionsHIV VaccineHIV-1 InfectionHIV-1-infectionPLWH

Phase 1

Study to Assess Safety and Ability to Induce Immune Responses of HIV-1 Vaccines M3 and M4 Given Alone or in Combination in HIV-infected Adults

CompletedNCT03844386

University of North Carolina, Chapel HillHIV-1 Infection

Start: 2019-04-22End: 2022-04-04Updated: 2022-08-09

Safety and Immunogenicity of HIV-1 Vaccines C62-M4 or C1C62-M3M4 in Persons With HIV-1 Suppressed on ART

CompletedNCT05604209

University of North Carolina, Chapel HillHIV-1-infection, HIV Vaccine

Start: 2022-10-13End: 2025-01-10Updated: 2025-08-24

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

RecruitingNCT06071767

National Institute of Allergy and Infectious Diseases (NIAID)HIV-1-infection

Start: 2024-04-01End: 2029-08-01Target: 36Updated: 2026-02-09

RV630 - Approach to Control HIV With Immune Enhancement and Vaccination (ACHIEV

RecruitingNCT06484335

Henry M. Jackson Foundation for the Advancement of Military MedicineAcute HIV Infection, ART, HIV Infections +1

Start: 2025-03-27End: 2027-08-01Target: 48Updated: 2025-09-16

Phase 2

Combination Vaccination and Broadly Neutralising Antibody Therapy in HIV

RecruitingNCT07054931

University of OxfordHIV

Start: 2025-09-05End: 2028-06-30Target: 48Updated: 2026-01-21

Related Papers

Safety, immunogenicity and effect on viral rebound of HTI vaccines combined with a TLR7 agonist in early-treated HIV-1 infection: a randomized, placebo-controlled phase 2a trial

Nature Communications2025-03-0416 citations

The Question of HIV Vaccine: Why Is a Solution Not Yet Available?

Journal of Immunology Research2024-01-0112 citations