MVA-BN-CV301

BIOLOGICAL2 trials

Sponsors

Patrick Boland, National Cancer Institute (NCI)

Conditions

Metastatic CancerMetastatic Colorectal CancerSolid Tumors

Phase 1

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta Trap/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

CompletedNCT04574583

National Cancer Institute (NCI)Metastatic Cancer, Solid Tumors

Start: 2020-11-24End: 2023-05-19Updated: 2025-02-03

Phase 2

A Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC

TerminatedNCT03547999

Patrick BolandMetastatic Colorectal Cancer

Start: 2018-06-26End: 2024-03-13Updated: 2025-07-22

Related Papers

HCRN GI16-288: A phase II trial of perioperative CV301 vaccination in combination with nivolumab and systemic chemotherapy for resectable hepatic-limited metastatic colorectal cancer—Preliminary efficacy and correlative results.

Journal of Clinical Oncology2023-01-241 citations