Mupirocin

DRUG18 trials

Sponsors

Wroclaw Medical University, University Hospital Muenster, Hillel Yaffe Medical Center, Region Skane, University of North Carolina, Chapel Hill

Conditions

Bacterial ColonizationCesarean SectionChronic RhinosinusitisChronic Rhinosinusitis (Diagnosis)Chronic Rhinosinusitis With Nasal PolypsCross InfectionCutaneous AbscessCystic Fibrosis

Early Phase 1

Thermosensitive Gel Nasal Spray With Stem Cell Exosomes, Mupirocin, and DNase I for Chronic Sinusitis

Not yet recruitingNCT07635433

The First Affiliated Hospital of Xinxiang Medical CollegeChronic Rhinosinusitis With Nasal Polyps

Start: 2026-07-01End: 2027-06-30Target: 108Updated: 2026-06-09

Phase 1

Topical Antibiotics in Chronic Rhinosinusitis

CompletedNCT03673956

Mayo ClinicChronic Rhinosinusitis (Diagnosis)

Start: 2018-09-26End: 2021-02-01Updated: 2022-04-20

Phase 2

Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)

TerminatedNCT01349192

University of North Carolina, Chapel HillCystic Fibrosis, Methicillin-resistant Staphylococcus Aureus

Start: 2011-04-30End: 2015-05-31Updated: 2017-05-15

STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)

CompletedNCT03489629

University of North Carolina, Chapel HillCystic Fibrosis

Start: 2018-04-03End: 2026-01-31Updated: 2026-02-17

Phase 3

Efficacy Study of Mupirocin on Infection After Coronary Artery Bypass Grafting

CompletedNCT01949935

Horizon Health NetworkSurgical Site Infections

Start: 2009-03-31End: 2013-05-31Updated: 2013-09-25

Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT

Hospital Italiano de Buenos AiresEpistaxis, Hereditary Hemorrhagic Telangiectasia

Start: 2017-06-30End: 2017-12-31Target: 40Updated: 2016-11-15

A non-commercial, randomized, open-label clinical trial to evaluate the efficacy of 1.8-cineole compared to mupirocin in the treatment of chronic rhinitis caused by carriage of methicillin-resistant Staphylococcus aureus (NOSE)

WithdrawnCTIS2025-521569-29-00

Wroclaw Medical Universitychronic active Staphylococcus aureus mono-infection/asymptomatic carriage in the nasal cavity

Target: 300Updated: 2026-04-07

Phase 4

Prophylaxis With Intranasal Mupirocin for Prevention of S. Aureus Infections

CompletedNCT00156377

University Hospital MuensterCross Infection, Staphylococcal Infections

Start: 2002-11-30Target: 1200Updated: 2010-05-25

Evaluation of a Staphylococcus Eradication Protocol for Patients Who Present to the ED With Cutaneous Abscess

CompletedNCT01537783

Tufts Medical CenterCutaneous Abscess

Start: 2011-09-30End: 2013-09-30Updated: 2017-04-13

The Use of Antibiotic Sinonasal Rinse After Sinus Surgery

CompletedNCT02218307

University of MiamiChronic Rhinosinusitis

Start: 2011-11-30End: 2015-06-30Updated: 2017-06-26

Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)

CompletedNCT02284555

Destiny Pharma PlcStaphylococcal Infection

Start: 2014-08-31End: 2014-11-30Updated: 2016-03-01

Staph Household Intervention for Eradication (SHINE)

CompletedNCT02572791

Washington University School of MedicineMRSA - Methicillin Resistant Staphylococcus Aureus Infection, Skin and Subcutaneous Tissue Bacterial Infections, Staphylococcus Aureus

Start: 2015-10-01End: 2024-12-01Updated: 2026-02-24

Unknown Phase

Effect of Intranasal Mupirocin on Rate of Staphylococcus Aureus Surgical Site Infection Following Cesarean Sections

Hillel Yaffe Medical CenterCesarean Section, Staphylococcus Aureus, Surgical Wound Infection

Start: 2010-07-31End: 2014-12-31Target: 400Updated: 2010-06-29

MESS-study MRSA Eradication Study Skåne

CompletedNCT01269541

Region SkaneThroatcarriers of MRSA

Start: 2011-03-01End: 2015-05-01Updated: 2017-08-22

Checklist to Prevent MRSA Surgical Site Infections

CompletedNCT02216227

VA Office of Research and DevelopmentSurgical Site Infection

Start: 2014-04-01End: 2021-02-28Updated: 2026-03-31

S. Aureus Decolonization in HPN Patients.

TerminatedNCT03173053

Radboud University Medical CenterMotility Disorder, Staphylococcus Aureus

Start: 2018-02-08End: 2021-10-14Updated: 2022-05-31

Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection

Phramongkutklao College of Medicine and HospitalPeritoneal Dialysis-related Infection

Start: 2021-12-01End: 2023-05-31Target: 60Updated: 2022-02-22

Bacterial Decolonization Within Dyads

CompletedNCT06541145

Duke UniversityBacterial Colonization

Start: 2024-08-21End: 2024-10-18Updated: 2026-06-03

Related Papers

Randomized clinical trial: Long-term Staphylococcus aureus decolonization in patients on home parenteral nutrition.

2023-03-172 citations

Strategies for the implementation of a nasal decolonization intervention to prevent surgical site infections within the Veterans Health Administration

Frontiers in Health Services2022-08-173 citations

Microbiological efficacy of early MRSA treatment in cystic fibrosis in a randomised controlled trial

UNC Libraries2020-04-22

Long-term Staphylococcus aureus decolonization in patients on home parenteral nutrition: study protocol for a randomized multicenter trial.

2018-06-284 citations

Microbiological efficacy of early MRSA treatment in cystic fibrosis in a randomised controlled trial

Thorax2016-11-1559 citations