Multiparametric Magnetic Resonance Imaging

PROCEDURE16 trials

Sponsors

University College, London, University College London Hospitals, OHSU Knight Cancer Institute, University of Southern California, ECOG-ACRIN Cancer Research Group

Conditions

Anatomic Stage IV Breast Cancer AJCC v8Brain NeoplasmClinical Stage IV Cutaneous Melanoma AJCC v8GliomaHealth Status UnknownMale Erectile DisorderMalignant Brain NeoplasmMetastatic Breast Carcinoma

Early Phase 1

18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases

CompletedNCT04752267

University of Southern CaliforniaAnatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Glioma +17

Start: 2021-02-15End: 2023-09-18Updated: 2024-05-24

rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

RecruitingNCT05852041

Northwestern UniversityProstate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8 +1

Start: 2023-06-07End: 2035-06-07Target: 40Updated: 2025-05-22

Phase 1

18F-FMAU PET/CT in Diagnosing and Characterizing Prostate Cancer

TerminatedNCT02809690

University of Southern CaliforniaProstate Neoplasm

Start: 2016-09-12End: 2021-07-21Updated: 2023-09-07

Phase 2

PSMA-Targeted 18F-DCFPyL PET/MRI for the Detection of Prostate Cancer

WithdrawnNCT04910425

Northwestern UniversityProstate Carcinoma

Start: 2023-06-17End: 2028-07-31Updated: 2025-10-21

Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial

RecruitingNCT06067269

Jonsson Comprehensive Cancer CenterProstate Adenocarcinoma, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8 +1

Start: 2024-03-28End: 2027-12-01Target: 95Updated: 2025-07-15

An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique

RecruitingNCT06865768

Emory UniversityProstate Carcinoma

Start: 2025-04-18End: 2029-12-31Target: 90Updated: 2025-06-24

Unknown Phase

Focal Therapy for Prostate Cancer Using HIFU

RecruitingNCT01194648

University College, LondonMale Erectile Disorder, Prostate Cancer, Therapy-related Toxicity +1

Start: 2011-06-29End: 2029-06-30Target: 354Updated: 2018-04-20

MRI in Diagnosing Prostate Cancer

University College London HospitalsProstate Cancer

Start: 2011-04-30Target: 714Updated: 2013-08-07

Transrectal MRI-Guided Biopsy in Identifying Cancer in Patients With Suspected Prostate Cancer

TerminatedNCT02501759

OHSU Knight Cancer InstituteHealth Status Unknown, Prostate Carcinoma

Start: 2015-05-31End: 2017-02-10Updated: 2019-04-03

High-Intensity Focused Ultrasound in Treating Participants With Intermediate and High-risk Prostate Cancer

WithdrawnNCT03514927

University of Southern CaliforniaProstate Cancer Stage I AJCC V6, Prostate Cancer Stage II, Prostate Cancer Stage III

Start: 2019-07-01End: 2022-07-01Updated: 2019-08-22

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

Active, not recruitingNCT03697148

ECOG-ACRIN Cancer Research GroupProstate Carcinoma

Start: 2019-02-11End: 2026-08-31Target: 852Updated: 2026-03-23

Multiparametric Magnetic Resonance Imaging Versus Fine Needle Aspiration Cytology for Parotid Gland Neoplasms

Davide Di SantoParotid Cancer, Parotid Neoplasm

Start: 2019-01-24End: 2021-12-31Target: 100Updated: 2019-02-22

MRI and Blood Biomarkers for the Prediction of Neurocognitive Decline Following Brain Radiation

Active, not recruitingNCT05087888

M.D. Anderson Cancer CenterBrain Neoplasm

Start: 2019-08-22End: 2027-12-31Updated: 2025-10-14

MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer

RecruitingNCT05438563

Mayo ClinicProstate Carcinoma, Stage II Prostate Cancer AJCC v8, Stage I Prostate Cancer AJCC v8

Start: 2022-04-06End: 2027-03-07Target: 100Updated: 2025-09-09

Prostate Resection After Microwave Ablation (PRAMA)

CompletedNCT06128525

University of Southern CaliforniaProstate Carcinoma

Start: 2023-11-10End: 2025-08-27Updated: 2025-11-28

Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

Not yet recruitingNCT07468903

Jonsson Comprehensive Cancer CenterProstate Adenocarcinoma, Stage II Prostate Cancer AJCC v8, Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8

Start: 2026-04-04End: 2032-04-04Target: 45Updated: 2026-03-19

Related Papers

A Pilot Study of <sup>18</sup> F‐rhPSMA‐7.3‐PET/MRI to Reduce Mischaracterization of Active Surveillance and Focal Therapy Candidates With Occult Higher Risk Disease

The Prostate2026-03-15

Detection of MRI‐Invisible Disease Using PSMA PET/CT in a Patient Considering Focal Therapy

Case Reports in Urology2025-01-011 citations

Regional Histopathology and Prostate MRI Positivity: A Secondary Analysis of the PROMIS Trial

Radiology2022-12-138 citations

Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study

Health Technology Assessment2018-07-01107 citations

MP38-07 SHOULD WE AIM FOR THE CENTRE OF AN MRI PROSTATE LESION? CORRELATION BETWEEN MPMRI AND 3-DIMENSIONAL 5MM TRANSPERINEAL PROSTATE MAPPING BIOPSIES FROM THE PROMIS TRIAL

The Journal of Urology2017-04-013 citations

MP70-02 CORRELATION OF MPMRI CONTOURS WITH 3-DIMENSIONAL 5MM TRANSPERINEAL PROSTATE MAPPING BIOPSY WITHIN THE PROMIS TRIAL PILOT: WHAT MARGINS ARE REQUIRED?

The Journal of Urology2017-04-01

Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study.

2017-01-202174 citations

The PROMIS study: A paired-cohort, blinded confirmatory study evaluating the accuracy of multi-parametric MRI and TRUS biopsy in men with an elevated PSA.

Journal of Clinical Oncology2016-05-2021 citations

Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study.

2012-04-17282 citations