Molidustat (BAY85-3934)

DRUG8 trials

Sponsors

Bayer

Conditions

AnemiaKidney DiseasesRenal Insufficiency, Chronic

Phase 1

Dose Escalation Study to Investigate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BAY85-3934 in Subjects With Chronic Kidney Disease (CKD)

CompletedNCT01679587

BayerKidney Diseases

Start: 2012-09-30End: 2013-07-31Updated: 2016-05-02

Phase 2

Long-term Pre-dialysis Extension in Europe and Asia Pacific

CompletedNCT02055482

BayerAnemia, Renal Insufficiency, Chronic

Start: 2014-06-24End: 2016-12-12Updated: 2017-11-22

Long Term Extension Study for the Maintenance Treatment of Anemia Associated With Chronic Kidney Disease (CKD) in Hemodialysis Subjects on Epoetin Alfa / Beta Treatment Versus BAY85-3934

CompletedNCT02064426

BayerAnemia, Renal Insufficiency, Chronic

Start: 2014-03-13End: 2016-11-16Updated: 2019-09-20

Phase 3

A Study of Molidustat for Maintenance Treatment of Renal Anemia in Non-dialysis Subjects

CompletedNCT03350347

BayerAnemia, Renal Insufficiency, Chronic

Start: 2017-12-13End: 2019-11-28Updated: 2021-01-29

A Study of Molidustat for Correction of Renal Anemia in Non-dialysis Subjects

CompletedNCT03350321

BayerAnemia, Renal Insufficiency, Chronic

Start: 2017-12-12End: 2019-10-11Updated: 2021-01-29

A Study of Molidustat for Correction of Renal Anemia in Dialysis Subjects

CompletedNCT03351166

BayerAnemia, Renal Insufficiency, Chronic

Start: 2018-01-22End: 2018-11-20Updated: 2021-01-29

A Study of Molidustat for Treatment of Renal Anemia in Peritoneal Dialysis Subjects

CompletedNCT03418168

BayerAnemia, Renal Insufficiency, Chronic

Start: 2018-02-22End: 2019-07-29Updated: 2021-01-29

Maintenance Treatment of Renal Anemia in Dialysis Subjects

CompletedNCT03543657

BayerAnemia, Renal Insufficiency, Chronic

Start: 2018-06-23End: 2019-12-24Updated: 2021-01-29

Related Papers

Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials

Clinical and Experimental Nephrology2023-04-242 citations

Molidustat for anemia correction in Japanese patients undergoing hemodialysis: a single‐arm, phase 3 study

Therapeutic Apheresis and Dialysis2021-01-289 citations

Molidustat for the treatment of renal anaemia in patients with non-dialysis-dependent chronic kidney disease: design and rationale of two phase III studies

BMJ Open2019-06-0123 citations

Molidustat for the treatment of renal anaemia in patients with dialysis-dependent chronic kidney disease: design and rationale of three phase III studies

BMJ Open2019-06-0122 citations