MK-8931

DRUG3 trials

Sponsors

Merck Sharp & Dohme LLC

Conditions

Alzheimer's DiseaseAmnestic Mild Cognitive ImpairmentProdromal Alzheimer's Disease

Phase 1

A Study of the Safety, Tolerability, and Pharmacodynamics of MK-8931 in Participants With Alzheimer's Disease (MK-8931-010 AM1 [P07820 AM1])

CompletedNCT01496170

Merck Sharp & Dohme LLCAlzheimer's Disease

Start: 2011-12-31End: 2012-06-30Updated: 2015-10-23

A Two-Part, Single-Dose Study of the Pharmacokinetics of MK-8931 in Subjects With Renal Insufficiency (MK-8931-009 [P08535])

CompletedNCT01537757

Merck Sharp & Dohme LLCAlzheimer's Disease

Start: 2012-03-31End: 2012-05-31Updated: 2015-01-26

An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)

CompletedNCT02910739

Merck Sharp & Dohme LLCAlzheimer's Disease, Amnestic Mild Cognitive Impairment, Prodromal Alzheimer's Disease

Start: 2016-10-11End: 2017-04-12Updated: 2018-10-01