MK-4827

DRUG5 trials

Sponsors

Tesaro, Inc., Merck Sharp & Dohme LLC

Conditions

Cancer: Solid TumorsChronic Lymphocytic LeukemiaGlioblastoma MultiformeLymphomaMantle-CellMelanomaNeoplasmsRecurrence of Solid Tumor

Phase 1

A Study of MK4827 in Participants With Advanced Solid Tumors or Hematologic Malignancies (MK-4827-001 AM8)

CompletedNCT00749502

Tesaro, Inc.Chronic Lymphocytic Leukemia, Solid Tumors, T-cell-prolymphocytic Leukemia

Start: 2008-09-30End: 2013-06-30Updated: 2013-07-25

A Study of MK-4827 in Combination With Standard Chemotherapy in Participants With Advanced Solid Tumors (MK-4827-008 AM1)

TerminatedNCT01110603

Tesaro, Inc.Cancer: Solid Tumors

Start: 2010-07-31End: 2011-07-31Updated: 2016-05-05

A Phase I Study of MK-4827 for Treatment of Solid Tumors (MK-4827-005)

TerminatedNCT01226901

Merck Sharp & Dohme LLCNeoplasms, Solid Tumors

Start: 2010-11-30End: 2011-11-30Updated: 2012-06-28

Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)

CompletedNCT01294735

Merck Sharp & Dohme LLCGlioblastoma Multiforme, Melanoma, Recurrence of Solid Tumor

Start: 2011-02-28End: 2012-05-31Updated: 2012-08-15

Phase 2

A Study of MK-4827 for the Treatment of Mantle Cell Lymphoma (MK-4827-002)

WithdrawnNCT01244009

Tesaro, Inc.Lymphoma, Mantle-Cell

Start: 2010-12-31End: 2013-08-31Updated: 2016-11-07

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