MitraClip

DEVICE18 trials

Sponsors

Abbott Medical Devices, University Medical Center Goettingen, Universiteit Antwerpen, Hospital Clinic of Barcelona, Montreal Heart Institute

Conditions

Acute Mitral RegurgitationAcute Myocardial InfarctionCardiovascular DiseasesEnd-stage Heart FailureFunctional Mitral RegurgitationHeart FailureMITRAL REGURGITATIONMitral Regurgitation

Phase 4

(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)

Hospital Clinic of BarcelonaMITRAL REGURGITATION

Start: 2015-09-30End: 2018-10-31Target: 30Updated: 2017-02-23

Unknown Phase

ACCESS-Europe A Two-Phase Observational Study of the MitraClip® System in Europe

CompletedNCT01288976

Abbott Medical DevicesMitral Valve (MV) Regurgitation

Start: 2008-10-31End: 2012-08-31Updated: 2018-11-07

A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation

TerminatedNCT01772108

Abbott Medical DevicesCardiovascular Diseases

Start: 2013-04-30End: 2015-01-31Updated: 2018-11-07

A Clinical Evaluation of the Safety and Effectiveness of the MitraClip System in the Treatment of Clinically Significant Functional Mitral Regurgitation

CompletedNCT02444338

University Medical Center GoettingenMitral Valve Insufficiency

Start: 2015-03-31End: 2024-04-19Updated: 2024-09-19

Belgian Mitraclip Registry

CompletedNCT02506387

Universiteit AntwerpenMitral Valve Insufficiency

Start: 2015-01-31End: 2024-12-31Updated: 2025-07-18

Evaluation of Outcomes of CRT and MitraClip for Treatment of Low Ejection Fraction and Functional Mitral Regurgitation in HF

WithdrawnNCT02985268

Montreal Heart InstituteFunctional Mitral Regurgitation, Heart Failure

Start: 2016-12-31End: 2020-02-29Updated: 2020-02-27

MitraClip in Acute Mitral Regurgitation

CompletedNCT03107455

Fundación Investigación Sanitaria en LeónAcute Myocardial Infarction, Mitral Regurgitation

Start: 2017-01-01End: 2021-12-01Updated: 2022-03-16

Mitral Valve Regurgitation Quantification From 3D Color Doppler Ultrasound - Standard of Care Data Collection

CompletedNCT03286088

Philips Electronics Nederland B.V. acting through Philips CTO organizationMitral Valve Regurgitation of Any Grade

Start: 2017-08-22End: 2019-12-31Updated: 2021-10-27

GIse Registry Of Transcatheter Treatment of Mitral Valve regurgitaTiOn (GIOTTO)

IRCCS Policlinico S. DonatoMitral Regurgitation

Start: 2016-02-01End: 2025-09-09Target: 1500Updated: 2023-12-05

A Pan-Canadian, Retrospective Evaluation of MitraClip Safety and Efficacy

CompletedNCT03592043

Population Health Research InstituteMitral Regurgitation

Start: 2019-01-01End: 2021-07-01Updated: 2021-09-02

Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial)

TerminatedNCT03891823

Montreal Heart InstituteVentricular Remodeling, Left

Start: 2019-03-08End: 2024-05-15Updated: 2024-05-30

Transcatheter Mitral Valve Repair as Bridge Therapy to Heart Transplantation

Scientific Institute San RaffaeleEnd-stage Heart Failure, Heart Failure, Mitral Regurgitation

Start: 2018-06-01End: 2021-06-30Target: 150Updated: 2020-03-26

Transcatheter Mitral Valvuloplasty Pilot Study

CompletedNCT04351984

Duk-Woo Park, MDMitral Regurgitation, Mitral Valve Insufficiency, Mitral Valve Regurgitation

Start: 2020-10-20End: 2021-12-31Updated: 2022-02-24

Mitral Regurgitation Treatment in Advanced Heart Failure

RecruitingNCT05292716

Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaHeart Failure, Mitral Regurgitation

Start: 2021-04-21End: 2026-04-21Target: 172Updated: 2024-08-05

Change in LVEF Following Transcatheter Mitral Edge-To-Edge Repair

Rabin Medical CenterMitral Regurgitation

Start: 2021-08-01End: 2022-08-01Target: 4000Updated: 2022-04-05

Early Transcatheter Mitral Valve Repair After Myocardial Infarction

RecruitingNCT06282042

Fundación para la Investigación Biosanitaria del Principado de AsturiasAcute Mitral Regurgitation

Start: 2024-12-24End: 2028-06-16Target: 250Updated: 2025-10-17

MitraClip in Patients With Heart Failure

RecruitingNCT06633159

The League of Clinical Research, RussiaMitral Regurgitation

Start: 2024-04-15End: 2025-12-31Target: 196Updated: 2024-10-09

In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment Algorithm

CompletedNCT06675448

Inova Health Care ServicesHeart Failure, Mitral Regurgitation, Valvular Heart Disease

Start: 2021-01-28End: 2026-08-18Updated: 2026-09-01

Related Papers

Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation

New England Journal of Medicine2024-08-31175 citations

Acute Reduction in Left Ventricular Function Following Transcatheter Mitral Edge‐to‐Edge Repair

Journal of the American Heart Association2023-06-2327 citations

Incidence, characteristics and functional implications of cerebral embolic lesions after the MitraClip procedure

EuroIntervention2015-02-0130 citations