Mitopure

DIETARY_SUPPLEMENT5 trials

Sponsors

Amazentis SA

Conditions

AgingHealthyHealthy AdultHealthy AgingHealthy DietMitochondrial DysfunctionMitochondrial Function, BioenergeticsMuscle Function

Phase 1

A Single and Multiple Dose Study of AMAZ-02 to Evaluate Safety and Pharmacokinetics in Elderly Subjects

CompletedNCT02655393

Amazentis SAAging, Mitochondrial Dysfunction, Muscle Function

Start: 2016-01-31End: 2016-12-31Updated: 2022-08-26

Unknown Phase

Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)

CompletedNCT03283462

Amazentis SAAging, Mitochondrial Function, Bioenergetics, Muscle Function

Start: 2018-02-15End: 2020-10-28Updated: 2022-08-22

Effects of Mitopure (Urolithin A) on Skeletal Muscle Function, Iron Metabolism and Endurance Performance

CompletedNCT04783207

Amazentis SAHealthy

Start: 2021-04-21End: 2023-08-30Updated: 2023-08-31

The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots

RecruitingNCT04985630

Amazentis SAHealthy, Healthy Aging, Healthy Diet

Start: 2021-08-30End: 2026-08-31Target: 250Updated: 2025-09-08

Cerebrospinal Fluid Kinetics of Urolithin A

Not yet recruitingNCT07517913

Amazentis SAHealthy Adult

Start: 2026-10-01End: 2027-10-01Target: 40Updated: 2026-09-09

Related Papers

Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners

Sports Medicine2025-08-211 citations

Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults

JAMA Network Open2022-01-20152 citations

Urolithin A enhances muscle performance in elderly and positively impacts biomarkers linked to cellular health

Innovation in Aging2021-12-01

Urolithin A, a Gut Microbiome Derived Metabolite Improves Mitochondrial and Cellular Health: Results from a Randomized, Placebo-controlled, Double-blind Clinical Trial (FS09-06-19)

Current Developments in Nutrition2019-06-011 citations

TRANSLATING UROLITHIN A BENEFITS ON MUSCLE MITOCHONDRIA TO HUMANS

Innovation in Aging2018-11-012 citations

ORALLY ADMINISTERED UROLITHIN A IS SAFE AND MODULATES MUSCLE AND MITOCHONDRIAL BIOMARKERS IN ELDERLY

Innovation in Aging2017-06-3010 citations