Minocycline hydrochloride capsule

DRUG4 trials

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University, Beijing Tiantan Hospital, Xiang Luo

Conditions

Acute Ischemic StrokeAnterior Circulation Brain InfarctionArterial OcclusionEndovascular ThrombectomyHelicobacter Pylori EradicationIschemic Stroke, AcuteMinocyclinePosterior Circulation

Phase 2

Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA)

Not yet recruitingNCT07594314

Xiang LuoAcute Ischemic Stroke, Anterior Circulation Brain Infarction, Endovascular Thrombectomy +2

Start: 2026-05-01End: 2028-12-01Target: 860Updated: 2026-05-20

Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)

RecruitingNCT07594301

Xiang LuoAcute Ischemic Stroke, Arterial Occlusion, Endovascular Thrombectomy +2

Start: 2026-05-19End: 2028-12-01Target: 234Updated: 2026-05-22

Phase 3

Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke

CompletedNCT05836740

Beijing Tiantan HospitalIschemic Stroke, Acute

Start: 2023-05-19End: 2024-08-15Updated: 2025-05-14

Phase 4

Effectiveness of Minocycline-Containing Bismuth Quadruple Therapy for Helicobacter Pylori Eradication

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityHelicobacter Pylori Eradication

Start: 2022-01-05End: 2022-12-05Target: 339Updated: 2022-01-13