Midazolam 2 mg

DRUG3 trials

Sponsors

Pfizer, Janssen Research & Development, LLC

Conditions

Crohn DiseaseHealthyHealthy VolunteersUlcerative Colitis

Phase 1

A Midazolam Drug Interaction Study With PF-04171327

CompletedNCT00987038

PfizerHealthy Volunteers

Start: 2009-09-30End: 2009-12-31Updated: 2009-12-08

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

CompletedNCT03058419

Janssen Research & Development, LLCHealthy

Start: 2017-03-14End: 2017-05-15Updated: 2017-06-08

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

TerminatedNCT03358706

Janssen Research & Development, LLCCrohn Disease, Ulcerative Colitis

Start: 2018-02-02End: 2021-11-22Updated: 2025-08-21

Related Papers

In Vitro and In Vivo Investigation of Potential for Complex CYP3A Interaction for PF‐00251802 (Dagrocorat), a Novel Dissociated Agonist of the Glucocorticoid Receptor

Clinical Pharmacology in Drug Development2017-11-075 citations