mFOLFOX6 (oxaliplatin, calcium folinate, and 5-FU)

DRUG3 trials

Sponsors

Sun Yat-sen University, Ye Xu

Conditions

Colorectal Cancer (Locally Advanced or Metastatic)Colorectal Cancer Microsatellite Stable (MSS)Hepatocellular Carcinoma

Phase 3

The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.

Sun Yat-sen UniversityHepatocellular Carcinoma

Start: 2017-07-01End: 2024-12-31Target: 290Updated: 2017-06-20

The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) Versus Adjuvant Transarterial Chemoembolization (TACE) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.

Sun Yat-sen UniversityHepatocellular Carcinoma

Start: 2017-07-01End: 2024-12-31Target: 162Updated: 2017-06-20

Phase 4

FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer

Not yet recruitingNCT07446465

Ye XuColorectal Cancer (Locally Advanced or Metastatic), Colorectal Cancer Microsatellite Stable (MSS)

Start: 2026-03-01End: 2027-01-31Target: 42Updated: 2026-03-03

Related Papers

Imaging-based surrogate classification for risk stratification of hepatocellular carcinoma with microvascular invasion to adjuvant hepatic arterial infusion chemotherapy: a multicenter retrospective study

International Journal of Surgery2024-07-245 citations

Postoperative adjuvant hepatic arterial infusion chemotherapy (HAIC) with FOLFOX to improve outcomes of patients with hepatocellular carcinoma with microvascular invasion: A prospective multicenter, phase 3, randomized, controlled clinical trial.

Journal of Clinical Oncology2022-06-014 citations

Postoperative Adjuvant Transarterial Infusion Chemotherapy with FOLFOX Could Improve Outcomes of Hepatocellular Carcinoma Patients with Microvascular Invasion: A Preliminary Report of a Phase III, Randomized Controlled Clinical Trial.

2020-05-1642 citations

Postoperative adjuvant transarterial infusion chemotherapy with FOLFOX could improve outcomes of hepatocellular carcinoma patients with microvascular invasion: A preliminary report of a phase III, randomized, controlled clinical trial.

Journal of Clinical Oncology2020-02-0111 citations