Methylphenidate HCl

DRUG6 trials

Conditions

ADHDAttention Deficit Disorder With HyperactivityAttention Deficit Hyperactivity DisorderDelayed Emergence From AnesthesiaHealthy

Phase 1

A Pharmacokinetics and Safety of Methylphenidate HCl in Healthy Japanese Adult Male Volunteers

CompletedNCT01202734

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.Healthy

Start: 2010-09-30End: 2010-11-30Updated: 2014-05-16

General Anesthesia Emergence Induced by Methylphenidate

CompletedNCT02327195

Nicoleta StoiceaDelayed Emergence From Anesthesia

Start: 2014-05-31End: 2018-01-31Updated: 2022-07-12

Phase 2

Effectiveness of Lobeline in Treating Symptoms of ADHD in Adult Patients

CompletedNCT00664703

Yaupon TherapeuticsAttention Deficit Disorder With Hyperactivity

Start: 2008-07-31End: 2010-01-31Updated: 2013-06-20

Phase 3

Long-term Safety and Effectiveness of OROS Methylphenidate HCl in Children With Attention Deficit Hyperactivity Disorder

CompletedNCT00269815

Alza Corporation, DE, USAAttention Deficit Hyperactivity Disorder

End: 1999-12-31Updated: 2011-06-14

Phase 4

Treatment of Severe Childhood Aggression (The TOSCA Study)

CompletedNCT00796302

Michael AmanAttention Deficit Disorder With Hyperactivity

Start: 2008-08-31End: 2012-11-30Updated: 2017-07-26

EEG Biomarkers for ADHD Stimulant Treatment

Not yet recruitingNCT07650643

Boston Children's HospitalADHD

Start: 2026-09-15End: 2031-08-31Target: 220Updated: 2026-06-16

2017-10-065 citations

Risperidone Added to Psychostimulant in Children with Severe Aggression and Attention-Deficit/Hyperactivity Disorder: Lack of Effect on Attention and Short-Term Memory

Journal of Child and Adolescent Psychopharmacology2016-06-2711 citations

Severely Aggressive Children Receiving Stimulant Medication Versus Stimulant and Risperidone: 12-Month Follow-Up of the TOSCA Trial.

2016-04-1331 citations

Comorbid Anxiety and Social Avoidance in Treatment of Severe Childhood Aggression: Response to Adding Risperidone to Stimulant and Parent Training; Mediation of Disruptive Symptom Response

Journal of Child and Adolescent Psychopharmacology2015-04-0114 citations

Participant Satisfaction in a Study of Stimulant, Parent Training, and Risperidone in Children with Severe Physical Aggression

Journal of Child and Adolescent Psychopharmacology2015-04-0110 citations

Risperidone added to parent training and stimulant medication: effects on attention-deficit/hyperactivity disorder, oppositional defiant disorder, conduct disorder, and peer aggression.

2014-06-1250 citations

What does risperidone add to parent training and stimulant for severe aggression in child attention-deficit/hyperactivity disorder?

2013-11-1886 citations

The treatment of severe child aggression (TOSCA) study: Design challenges.

2011-11-1028 citations

Pharmacokinetics and therapeutic effect of OROS methylphenidate under different breakfast conditions in children with attention-deficit/hyperactivity disorder.

2011-06-0113 citations