Methylnaltrexone (MNTX)

DRUG3 trials

Sponsors

Bausch Health Americas, Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Conditions

Healthy VolunteersOpioid-induced ConstipationRenal Impairment

Phase 1

Effect of Methylnaltrexone (MNTX) on Electrocardiogram (ECG) Parameters and Cardiac Repolarization

CompletedNCT01363323

Bausch Health Americas, Inc.Healthy Volunteers

Start: 2004-11-30End: 2005-02-28Updated: 2019-11-29

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

CompletedNCT01367509

Bausch Health Americas, Inc.Renal Impairment

Start: 2004-03-31End: 2005-06-30Updated: 2019-11-27

Phase 2

Study of Methylnaltrexone in Opioid-Induced Constipation Patients

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Opioid-induced Constipation

Start: 2015-04-30End: 2017-04-30Target: 198Updated: 2015-10-14