Methoxsalen

DRUG13 trials

Sponsors

Medac Gesellschaft fuer klinische Spezialprapaerate mbH, Therakos, National Center for Research Resources (NCRR), Millennix, Mallinckrodt

Conditions

Chronic Graft vs. Host DiseaseEpidermolysis Bullosa AcquisitaGraft Versus Host DiseaseGraft vs Host DiseaseGraft-Versus-Host DiseaseGraft-versus-Host DiseaseHIV InfectionsHematological Malignancies

Phase 1

Extracorporal Photopheresis Pilot Study

Hospices Civils de LyonHematological Malignancies

Start: 2009-04-30End: 2015-09-30Target: 20Updated: 2013-04-24

Phase 2

Phase II Pilot Study of Extracorporeal Phototherapy for Epidermolysis Bullosa Acquisita

CompletedNCT00004359

National Center for Research Resources (NCRR)Epidermolysis Bullosa Acquisita

Start: 1996-02-29Target: 10Updated: 2005-06-24

Chemotherapy and Photodynamic Therapy in Treating Patients With Cutaneous T-Cell Lymphoma

MillennixLymphoma

Start: 2001-02-28Updated: 2013-12-18

Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease

CompletedNCT00054613

MallinckrodtGraft-versus-Host Disease

Start: 2002-06-30End: 2004-03-31Target: 72Updated: 2017-08-16

Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease

CompletedNCT00054600

MallinckrodtGraft-versus-Host Disease

Start: 2002-06-30End: 2004-06-30Target: 60Updated: 2017-08-16

Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Rheumatoid Arthritis

CompletedNCT00221000

MallinckrodtRheumatoid Arthritis

Start: 2003-08-31End: 2006-11-30Updated: 2016-10-19

Addition of Etanercept and Extracorporeal Photopheresis (ECP) to Standard Graft-Versus-Host Disease (GVHD) Prophylaxis in Stem Cell Transplant

CompletedNCT00639717

University of Michigan Rogel Cancer CenterGraft Versus Host Disease

Start: 2009-03-31End: 2016-04-30Updated: 2017-08-01

Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD

TerminatedNCT02322190

National Cancer Institute (NCI)Chronic Graft vs. Host Disease, Graft-Versus-Host Disease, Graft vs Host Disease

Start: 2014-12-20End: 2019-10-31Updated: 2020-03-12

Study of Photopheresis in the Treatment of Erythrodermic MF and SS

WithdrawnNCT03563040

European Organisation for Research and Treatment of Cancer - EORTCLymphoma, T-Cell, Cutaneous, Mycosis Fungoides/Sezary Syndrome

Start: 2020-12-01End: 2026-06-01Updated: 2021-09-08

A Randomised, Open label, Controlled, Multicentre, Phase 2 Trial of First line Treatment with Mesenchymal Stromal Cells MC0518 Versus Best Available Therapy in Paediatric Participants with Steroid refractory Acute Graft versus host Disease After Allogeneic Stem Cell Transplantation (BALDER Trial)

RecruitingCTIS2023-503952-28-00

Medac Gesellschaft fuer klinische Spezialprapaerate mbHSteroid refractory Acute Graft versus host Disease

Start: 2023-11-13Target: 54Updated: 2025-05-21

EPIC- Extracorporeal Photopheresis (ECP) for Immune-related Colitis

WithdrawnNCT06646016

Therakos LLCImmune-related Colitis

Start: 2025-12-15End: 2027-02-19Updated: 2025-12-26

Phase 3

Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Participants With Steroid Refractory Acute Graft Versus Host Disease

TerminatedNCT02524847

Therakos, Inc., a Mallinckrodt CompanySteroid Refractory Acute Graft Versus Host Disease

Start: 2016-01-20End: 2019-07-16Updated: 2020-09-11

Unknown Phase

The Therakos UVAR Photopheresis System in the Treatment of AIDS-Related Complex

CompletedNCT00002011

TherakosHIV Infections

Updated: 2005-06-24

Related Papers

Efficacy of Methoxsalen Sterile Solution in Conjunction with the Therakos® Cellex® Photopheresis System in Pediatric Patients with Steroid-Refractory Acute GvHD: Interim Analysis

Blood2019-11-13

A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease.

2008-07-11235 citations