Methotrexate Sodium

DRUG4 trials

Sponsors

National Cancer Institute (NCI), Seoul National University Hospital, Seoul National University Bundang Hospital, Hospital de Clinicas de Porto Alegre

Conditions

Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Drug InteractionDrug InteractionsEctopic PregnancyRecurrent Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic Leukemia

Phase 1

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects

CompletedNCT05575297

Seoul National University HospitalDrug Interaction

Start: 2021-12-20End: 2022-05-09Updated: 2022-10-12

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects

Seoul National University Bundang HospitalDrug Interactions

Start: 2023-08-21End: 2024-11-24Target: 10Updated: 2023-10-31

Phase 2

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Active, not recruitingNCT02143414

National Cancer Institute (NCI)Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 +2

Start: 2015-06-30End: 2027-01-26Updated: 2026-04-03

Phase 4

Use of Letrozole for Ectopic Pregnancy

RecruitingNCT06354439

Hospital de Clinicas de Porto AlegreEctopic Pregnancy

Start: 2024-03-27End: 2026-12-31Target: 130Updated: 2024-04-09

Related Papers

Dasatinib/prednisone induction followed by blinatumomab/dasatinib in Ph+ acute lymphoblastic leukemia

Blood Advances2022-11-0267 citations