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methotrexate (intrathecal)

DRUG2 trials

Sponsors

Johann Wolfgang Goethe University Hospital, Novartis Pharmaceuticals

Conditions

Acute Lymphoblastic LeukemiaLeukemia, Lymphoblastic, Acute, Philadelphia-PositiveLymphoid Blastic Phase of Chronic Myeloid LeukemiaPhiladelphia Chromosome Positive Acute Lymphoblastic LeukemiaPhiladelphia Positive Acute Lymphoblastic Leukemia

Phase 1

Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)
Not yet recruitingNCT07387926
Novartis PharmaceuticalsAcute Lymphoblastic Leukemia, Leukemia, Lymphoblastic, Acute, Philadelphia-Positive, Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Start: 2026-03-26End: 2035-12-12Target: 50Updated: 2026-02-04

Phase 2

Study Comparing Imatinib With Chemotherapy as Induction in Elderly Patients With Philadelphia Positive Acute Lymphoblastic Leukemia (ALL)
NCT00199186
Johann Wolfgang Goethe University HospitalLymphoid Blastic Phase of Chronic Myeloid Leukemia, Philadelphia Positive Acute Lymphoblastic Leukemia
Start: 2002-03-31Updated: 2007-10-19