Methadone hydrochloride

DRUG17 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID), M.D. Anderson Cancer Center, NCIC Clinical Trials Group, Nationwide Children's Hospital, Roswell Park Cancer Institute

Conditions

Brain and Central Nervous System TumorsCandidiasisChildrenChildren, OnlyChronic Myeloproliferative DisordersCleft PalateDegenerative Disc DiseaseHIV Infections

Early Phase 1

Epidural Methadone in Healthy Volunteers

CompletedNCT03525509

simon.haroutounianPain, Acute

Start: 2018-06-04End: 2019-08-30Updated: 2019-09-18

Phase 1

Interactions of HIV Protease Inhibitors and Methadone in HIV-Infected Patients

CompletedNCT00000906

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections

End: 2000-09-30Target: 12Updated: 2021-11-04

A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone

CompletedNCT00000788

National Institute of Allergy and Infectious Diseases (NIAID)Candidiasis, HIV Infections

End: 1994-06-30Target: 24Updated: 2021-11-03

Methadone Effects on Zidovudine (ZDV, AZT) Disposition

CompletedNCT00000800

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections

End: 1998-10-31Target: 15Updated: 2021-11-04

Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain

TerminatedNCT00930332

NCIC Clinical Trials GroupNausea and Vomiting, Pain, Sleep Disorders +1

Start: 2010-06-17End: 2012-01-06Updated: 2024-02-12

Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation

CompletedNCT02531906

Roswell Park Cancer InstituteHead and Neck Squamous Cell Carcinoma, Pain, Stomatitis

Start: 2015-04-24End: 2018-06-14Updated: 2022-07-25

Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions

The Methodist Hospital Research InstituteDegenerative Disc Disease, Spondylolisthesis, Lumbar Region

Start: 2020-02-11End: 2021-12-31Target: 150Updated: 2020-01-29

MethaLoad Dose-Finding Study

RecruitingNCT06877858

University of PennsylvaniaOpioid Use Disorder (OUD)

Start: 2025-09-25End: 2027-07-31Target: 24Updated: 2025-10-14

Phase 2

Methadone vs Magnesium in Spinal Fusion

CompletedNCT01795495

Nationwide Children's HospitalIdiopathic Scoliosis

Start: 2013-09-30End: 2016-09-30Updated: 2018-02-08

Phase 3

Intraoperative Methadone in Children Undergoing Surgery

TerminatedNCT04680286

University of AarhusChildren, Only, Pain, Acute, Pain, Postoperative

Start: 2020-11-16End: 2024-02-01Updated: 2024-02-28

Intraoperative Methadone for the Prevention of Postoperative Pain

RecruitingNCT05831345

Brugmann University HospitalOrthopedic Surgery

Start: 2023-02-28End: 2025-12-31Target: 80Updated: 2025-02-07

Methadone in TKA for Post-op Pain and Opioid Reduction

RecruitingNCT07226076

Medical University of South CarolinaPost Operative Pain

Start: 2026-01-08End: 2027-01-15Target: 162Updated: 2026-02-04

Phase 4

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

TerminatedNCT02989597

Montefiore Medical CenterPain, Postoperative

Start: 2017-07-29End: 2020-11-10Updated: 2023-05-22

Perioperative Methadone Compared to Placebo in Elderly Hip Fracture Patients

CompletedNCT06086171

University of Southern DenmarkHip Fractures, Methadone

Start: 2023-11-10End: 2025-02-21Updated: 2025-03-18

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

RecruitingNCT06962306

Duke UniversityChildren, Cleft Palate, Pain +2

Start: 2025-06-04End: 2027-07-04Target: 60Updated: 2025-06-13

Unknown Phase

A Study of Azidothymidine Plus Methadone in Patients With AIDS and AIDS Related Complex (ARC)

CompletedNCT00001008

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections

Target: 18Updated: 2011-03-14

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

TerminatedNCT00726830

M.D. Anderson Cancer CenterBrain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia +8

Start: 2009-03-31End: 2010-10-31Updated: 2020-09-24

Related Papers

Perioperative methadone compared to placebo in elderly hip fracture patients: a study protocol for a randomized controlled trial (MetaHip trial).

2024-12-20